Cardiovascular System Flashcards
functions of blood
▫transport dissolved substances ▫regulate ph and ions ▫restriction of fluid loss due to injury ▫defense against pathogens ▫stabilize body temp
fractionation
separating blood for analysis
plasma makes up what % of blood volume
50-60
how plasma differs from interstitial fluid
▫levels of oxygen and carbon dioxide
▫concentration of proteins
plasma consists of
▫water
▫proteins
▫other solutes
red blood cells
transport oxygen
platelets
involved in clotting process
hemopoiesis
process of making formed elements
3 types of formed elements
▫red blood cells
▫white blood cells
▫platelets
what makes up the majority of formed elements
red blood cells
rouleaux
stack of red blood cells
red blood cells lack what
nuclei, mitochondria, and ribosomes
stages of red blood cell maruration
▫myeloid stem cell ▫proerythroblast ▫erythrocyte ▫reticulocyte ▫mature red blood cell
erythropoeitin
hormone that stimulates red blood cell production when oxygen levels are low
hemoglobin
protein that transports respiratory gases
structure of hemoglobin is made of
4 subunits, each containing a molecule of heme
oxyhemoglobin
plenty of oxygen
deoxyhemoglobin
low oxygen
function if white blood cells
▫defend against pathogens
▫remove toxins and waste
▫attack abnormal cells
types of white blood cells
▫neutrophils ▫eosinophils ▫basophils ▫monocytes ▫lymphocytes
neutrophils
active in attacking and engulfing bacterial pathogens
eosinophils
▫attack large parasites by excreting toxic compounds
▫sense give to allergens
basophils
dialate blood vessels and help prevent clottinf
monocytes
▫engulf large particles and pathogens
▫secrete substances that attract immune system cells
lymphocytes
identify and destroy specific pathogens
types of lymphocytes
▫t cells
▫b cells
▫natural killer cells
t cells
detect and destroy cells w/o use of antibodies
b cells
detect and destroy pathogens using antibodies
natural killer cells
detect and destroy abnormal tissue cells
3 functions of platelets
▫release important clotting chemicals
▫temporarily path damaged vessel walls
▫contract tissues after clot formation
thrombocytopoiesis
production of platelets
thrombocytopenia
abnormally low platelet count
thrombocytosis
abnormally high count
3 phases of hemostasis (stop bleeding)
▫vascular phase
▫platelet phase
▫coagulation phase
vascular phase
blood vessel damaged contricts
platelet phase
platelets signaled and form platelet plug to close openeing
coagulation phase
platelets contract, pulling ends of hole together, fibrin form over plug
thrombus
abnormal blood clot
embolus
when clot moves to another place
cerebral embolism
blood clot goes to brain
pericardium
loose fitting sac around the heart that anchors it, prevents over filling, and reduces friction
fibrous pericardium
tough, loose fitting, elastic layer
pericardium is composed of
▫fibrous pericardium
▫two layers of serous pericardium
parietal layer of serous pericardium
lines inside of pericardium
visceral layer of serous pericardium
adheres of outside of heart
epicardium
outer wall of heart
myocardium
cardiac muscle layer forming bulk of heart
endocardium
inner endothelium layer of heart
layer if heart walls from outside to inside
▫epicardium
▫myocardium
▫endocardium
layers of pericardium from outside in
▫fibrous
▫parietal
▫visceral
atria
two superior chambers of the heart that receive blood from body
ventricles
two inferior chambers that pump blood out
atroventricular valves
between atria and ventricles
semilunar valves
between ventricles and arteries
tricuspid valve
between r atrium and r ventricle
chordae tendinae
connects tricuspid to muscle
bicuspid valve
between L atrium and L ventircle
pulmonary semilunar valve
between r ventricle and pulmonary trunk
aorta semilunar valve
between L ventricle and aorta
path of blood flow starting at right atrium
▫r atrium through tricuspid to r ventricle
▫r ventricle through pulmonary SL valve to pulmonary arteries
▫pulmonary arteries to lungs
▫lungs to pulmonary veins
▫pulmonary veins to L atrium
▫L atrium through bicuspid to L ventricle
▫L ventricle through aortic SL valve to aorta
▫aorta through arteries to body organs
▫body organs through veins to vena cava
▫vena cava to R atrium
coronary circularion
heart to heart
pulmonary circulation
heart to lungs
systemic circulation
heart to body
heart is innervated by what nerve
vagus nerve
conduction step 1
sinoarterial node sends signal to L atrium so both atria contract at the same time
conduction step 2
▫sinoarterial node passes signal to atrioventricular node.
▫signal travels from atria to ventricle via the bundle of his
conduction step 3
▫bundle of his carries signal towards apex
▫signal transfers to purkinje fibers which make cells contract around ventricle
systole
contraction
diastole
relaxation
normal bp
120/80
3 layers of blood vessels(out to in)
▫tunica adventita
▫tunica media
▫tunics intima
tuncia adventitia
fibrous connective tissue that holds vessels open
tunica media
smooth muscle/elastic CT that contracts and dialates blood vessels
tunica intima
endothelium layer containing valves in veins
arteries
carry blood away from the heart
veins
carry blood towards the heart
arterioles
small artery
venules
small veins
capillaries
where arterial system switches to the venous system
precapillary sphincter
circular valve like muscle at arteriole-capillary junction
vasoconstriction
narrowing of vessel
vasodialation
expanding blood vessel
aorta
▫largest artery
▫leaves L ventricle
pulmonary artery
▫leaves R ventricle
▫carries blood to lungs
pulmonary veins
returns blood from lungs
vena cava
returns blood from rest of body to right atrium
coronary arteries
supply blood to heart itself
brachiocephalic artery
branches into R subclavian and R common carotid
L common carotid
supplies left side of head
L subclavian artery
supplies to arm
varicose veins
when blood pools in veins
SADS
heart unexplainable stops working
heart murmers
unusual sound caused by valve issue
mitral valve prolapse
valve shifts out of place shifts and causes a clicking sound
myocardial infarction
obstruction in coronary artery
arteriosclerosis
deposits of fatty material that reduce blood flow
aneurism
a localized blood filled balloon in the wall of a vessel
stroke
blood flow to brain is cut off
hemorrhagic stroke
aneurysm that bursts
ischemic stroke
blood vessel is blocked
average temo of blood
38°C
average ph of blood
7.35-7.45
erythrocyte
red blood cell
leukocyte
white blood cell
thrombocyte
platelet
how many red blood cells in 1 drop of blood
4.2-6.3 million
how many white blood cells in one micro liter
5000-10000
how many platelet in one microliter
150,000-500,000
Rh factor
another set of proteins in he blood
group of cells that act as hearts pace maker
sinoarterial node
coronary
heart
subclavian (R/L)
arms
common carotid (R/L)
head and neck
intercostal
cheat wall
gonadal
testes/ovaries
superior mesenteric
small intestine and upper large intestine
inferior mesenteric
lower large intestine
renal
kidney
hepatic
liver
splenic
spleen
left gastirc
stomach
external illiac
legs
internal illiac
pelvic organs
what % of formed elements are red blood cells
99%
three classes of proteins in plasma
▫albumins
▫globulins
▫fibrinogen
albumin
transport substances such of fatty acids and hormones
globulins
transport globulins
fibrinogen
form clots and produce fibrin