Cardiovascular Physiology Flashcards
Characteristics of cardiac muscle tissue
Made up of cardiac cells –> individual cells but work as one unit
Has intercalated discs: connects ends of muscle cells to each other
What is found in the intercalated discs?
Desmosomes: type of cell junction that holds fibers together
Gap junctions: allow action potentials to conduct from 1 muscle fibre to its neighbour
Importance of the SA node
Natural pacemaker of the heart –> initiates AP 100/min
Nerve impulses from ANS + hormones can modify the speed
APs from SA node go throughout both atria via gap junctions + excite contractile fibers
Importance of the AV node
Located in the interatrial septum
AP slows down here (has smaller fibers + less gap junctions)
Why is it important that the AP slows down at the AV node?
The delay allows for the atria to empty their blood into the ventricles
What happens if the SA node gets damaged?
AV node picks up pace making tasks (at a slower rate)
Purpose of AV bundle
So AP can conduct from atria –> ventricles
Where are the R + L bundle branches found?
They extend down through the interventricular septum toward the heart apex
Purpose of purkinje fibers
APs rapidly conduct from heart apex –> ventricular myocardium
How to inotropes work?
A substance that alters the movement of calcium through its channels (affects strength of heart contractions)
Positive inotrope = more calcium (epinephrine)
Negative inotrope = less calcium
What does the P wave represent?
Small wave –> atrial depolarization
What does the QRS complex represent?
Depolarization of the ventricles (repolarization of the atria also occur; masked)
What does the T wave represent?
Ventricular repolarization
De/repolarization and heart muscle
Depolarization = contraction of heart muscle
Repolarization = relaxation of heart muscle
S1 heart sound
AV valve closure