Cardiovascular

Question 1

lung macrophages containing golden cytoplasmic granules that turn dark blue w. Prussian blue staining, think ?? caused by ??
hemosiderosis caused by left ventricular dysfunction

Answer 1

-LHF causes increased pulmonary cap pressure and pulmonary edema–>extravasation of RBCs and alveolar hemorrhage, RBCs phagocytksed by macrocytes and iron from HGB converted to hemosiderin

Question 2

myxomatous changes (pathologic weakening of connective tissue and pooling of proteoglycans in media and ),and intact intima in large arteries

Answer 2

Myxomatous changes (pathologic weakening of connective tissue) in the media of large arteris are found in cystic medial degeneration. Medial degeneration is characterized by the gragmentation of elastic tissue (basket weave pattern comparted to normal( and separation of the elastic fibromuscular components of the tunica medai by small, cleft like spaces taht beocme filled with amorphous extracellular matrix

Question 3

Renal artery stenosis hX

Answer 3

crowded glomeruli , tubular atrophy, interstitial fibrosis’ focal inflammatory infiltrate