Cardiomyopathy Flashcards
What can cause Hypertrophic CM
- AD Mutation of Sarcomere Proteins (Troponin T and Myosin B)
- Exercise
- Aortic stenosis
What can cause Hypertrophic CM
- AD Mutation of Sarcomere Proteins (Troponin T and Myosin B)
- Exercise
- Aortic stenosis
What is the pathology of Hypertrophic CM
Thick non compliant heart = Impaired diastolic filling = Decrease CO
What are the presentations of Hypertrophic CM
- Sudden death in young
- Chest pain
- Palpitation
- SOB
- Syncope
How is Hypertrophic CM Investigated and Diagnosed
Abnormal ECG
Genetic testing
Gold = ECHO
How is hypertrophic CM treated
BB
CCB
Amiadorone (Anti arrhythmia)
What can cause dilated CM
- AD Mutation of cytoskeleton gene
- IHD
- Alcohol
What is the pathology of Dilated CM
Thin cardiac walls can’t contract = Low CO
What are the symptoms of Dilated CM
SOB
Heart fail
AF
Thromboemboli
What are the investigations and how is Dilated CM Diagnosed
ECG
ECHO = Gold
How is Dilated CM treated
Treat cause (AF and Heart fail)
What causes Restrictive CM
- Granulomatous disease (Sarcoidosis/Amyloidosis)
- Idiopathic
- Post MI
What is the pathology of Restrictive CM
Rigid fibrotic myocardium that fills poorly = Low CO
What are the presentations of Restrictive CM
Dyspnoea S3 and S4 Sound Oedema Heart Fail Narrow Pulse pressure
How is restrictive CM Investigates and Diagnosed
ECG
ECHO
Dx = Cardiac Catheterisation