Cardio11 Flashcards

Baroreceptors & Chemoreceptors CIrculation Normal pressures

1
Q

Receptors on the Aortic Arch transmit via the ______ nerve to the _________________.

A

Vagus n.

Solitary nucleus of medulla

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2
Q

What do the receptors on the aortic arch respond to?

A

INcreased BP (ONLY thing)

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3
Q

Receptors on the Carotid sinus transmits via the ______________ n. to the _________________.

A

Glossopharyngeal n.

Solitary nucleus of medulla

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4
Q

What do the receptors on the carotid sinus respond to?

A

INcrease & DEcrease in BP

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5
Q

How do baroreceptors respond to a Carotid massage?

A

INcreased pressure on Carotid a.
INcreased Stretch
INcreased Afferent Baroreceptor firing
DEcreased BP

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6
Q

What are the stimuli for the peripheral chemoreceptors located on the carotid and aortic bodies?

A

DEcreased (<60 mmHg)
INcreased PCO2
DEcreased pH of blood

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7
Q

What are the central chemoreceptors stimulated by?

A

Changes in pH & PCO2 of brain interstitial fluid, which in turn are influenced by arterial CO2

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8
Q

T/F - Central chemoreceptors do not directly respond to PO2.

A

True

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9
Q

What organ receives the largest share of systemic cardiac output?

A

Liver

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10
Q

Which organ has the highest blood flow per gram of tissue?

A

Kidney

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11
Q

In the heart, O2 demand is met by:

- INcreased extraction of O2 or INcreased coronary blood flow?

A

INcreased coronary blood flow

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12
Q

Pulmonary Capillary Wedge pressure (PCWP) is a good approximation of ________ pressure.

A

Left atrial pressure

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13
Q

PCWP > LV diastolic pressure, is seen in what type of heart condition?

A

Mitral stenosis

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14
Q

How do you measure PCWP?

A

Swan-Ganz catheter

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15
Q

How does blood flow to an organ remain constant over a wide range of perfusion pressures?

A

Autoregulation

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16
Q

Factors determining Autoregulation in the Heart.

A

Local metabolites (Vasodilatory):

  • CO2
  • Adenosine
  • NO
17
Q

Factors determining Autoregulation in the Brain.

A
Local metabolites (Vasodilatory):
 - CO2 (pH)
18
Q

Factors determining Autoregulation in the Kidneys.

A

Myogenic & Tubuloglomerular feedback

19
Q

Factors determining Autoregulation in the Lungs.

A

Hypoxia causes VasoConstriction

20
Q

Factors determining Autoregulation in the Skeletal Muscle.

A

Local metabolites:

  • Lactate
  • Adenosine
  • K+
21
Q

Factors determining Autoregulation in the Skin.

A

SYmpathetic stimulation most important mechanisms – Temperature control

22
Q

What is unique about the pulmonary vasculature?

A

Hypoxia causes Vasoconstriction, so that only well-ventilated areas are perfused

*In other organs hypoxia causes VasoDilation