Cardio1 Flashcards
Embryology
Truncus arteriosus (TA) gives rise to.
Ascending aorta & Pulmonary Trunk
Bulbus cordis gives rise to.
Smooth parts (outflow tract) of left and right VENTRICLES
The Primitive Ventricle gives rise to.
Trabeculated left and right Ventricles
The Primitive Atria gives rise to.
Trabeculated left and right Atria
The Left Horn of Sinus Venosus (SV) gives rise to.
Coronary sinus
The Right Horn of the Sinus Venosus (SV) gives rise to.
Smooth part of Right Atrium
The Right Common Cardinal Vein & Right Anterior Cardinal Vein give rise to.
Superior Vena Cava (SVC)
Describe the development of the Truncus Arteriosus.
Neural Crest Migration
Truncal & Bulbar ridges Spiral and Fuse
Form the Aorticopulmonary (AP) Septum
Ascending Aorta & Pulmonary Trunk
What pathologies are associated with the Truncus Arteriosus?
Transposition of the Great Vessels - failure to spiral Tetralogy of Fallot - skewed AP septum development Persistant TA - Partial AP septum development
3 stages of Interventricular Septum Development.
1-Muscular ventricular septum forms
*opening - interventricular foramen
2-AP septum Rotates and fuses with muscular ventricular septum; closes interventricular septum
*forms membranous interventricular septum
3-Growth of Endocardial Cushions separates Atria from Ventricles
What is Eisenmenger’s syndrome?
Membranous septal defect that causes an initial left-to-right shunt, which later reverses to a right-to-left shunt due to onset of Pulmonary Hypertension
Interatrial Septum Development: Step 1
-Foramen primum narrows as septum prium grows toward _______________.
Endocardial cushions
Interatrial Septum Development: Step 2
-Perforations in septum primum form ____________. (forament primum disappears)
Foramen Secundum
Interatrial Septum Development: Step 3
-Foramen secundum maintains _________ shunt as septum secundum begins to grow.
Right-to-Left
Interatrial Septum Development: Step 4
-Septum secundum contains a ______________.
Permanent opening (Foramen Ovale)
Interatrial Septum Development: Step 5
-Foramen secundum enlarges and upper part of ____________ degenerates.
Septum primum
Interatrial Septum Development: Step 6
-Remaining portion of septum primum forms valve of ______________.
Foramen Ovale
Interatrial Septum Development: Step 7
-Septum secundum and septum primum fuse to form the __________.
Atrial Septum
Interatrial Septum Development: Step 8
-Foramen ovale usually closes soon after birth because of increased ______ pressure.
Left Atrium
Failure of the septum primum and septum secundum to fuse after birth.
Patent Foramen Ovale
