cardio infection Flashcards
amoxicillin
β-lactam antibiotics
amoxicillin
Bacterial penicillin-binding proteins/transpeptidase enzymes
amoxicillin
Inhibit cross-linking of NAMA/NAG peptide chains in the peptidoglycan bacterial cell wall
amoxicillin good for what infection
respiratory infections, UTI, otitis media
amoxicillin bad side effects
Hypersensitivity reactions
Antibiotic associated diarrhoea
Encephalopathy due to cerebral irritation
Maculopapular rash
when would a patient get a rash with amoxicillin
patients with glandular fever
Benzylpenicillin good for what infection
bacterial meningitis
Flucloxacillin good for what infection
severe infection, pseudomonas
gentamicin
Aminoglycoside antibiotics
gentamicin
Bacterial 30s ribosomal subunit
how does gentamicin work against anaerobes
it dosent - requires oxygen
gentamicin important side effects
Nephrotoxicity
Ototoxicity
Antibiotic-associated diarrhoea/colitis
vancomycin drug class
Glycopeptide antibiotics
vancomycin target
NAMA and NAG peptides
vancomycin moa
irreversibly block the elongation of peptidoglycan chains by preventing the incorporation of NAMA and NAG peptide subunits
vancomycin bad side effects
Nephrotoxicity
Ototoxicity
Blood disorders
Severe hypotension, anaphylactoid reaction on rapid infusion
Benzylpenicillin drug class
Transpeptidase inhibitor
Benzylpenicillin also known as
Penicillin G
Benzylpenicillin binds to
penicillin binding proteins
Benzylpenicillin inhibits
call wall synthesis
good thing about Benzylpenicillin
stable against hydrolysis by a variety of beta-lactamases
