cardio infection Flashcards

1
Q

amoxicillin

A

β-lactam antibiotics

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2
Q

amoxicillin

A

Bacterial penicillin-binding proteins/transpeptidase enzymes

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3
Q

amoxicillin

A

Inhibit cross-linking of NAMA/NAG peptide chains in the peptidoglycan bacterial cell wall

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4
Q

amoxicillin good for what infection

A

respiratory infections, UTI, otitis media

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5
Q

amoxicillin bad side effects

A

Hypersensitivity reactions
Antibiotic associated diarrhoea
Encephalopathy due to cerebral irritation
Maculopapular rash

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6
Q

when would a patient get a rash with amoxicillin

A

patients with glandular fever

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7
Q

Benzylpenicillin good for what infection

A

bacterial meningitis

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8
Q

Flucloxacillin good for what infection

A

severe infection, pseudomonas

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9
Q

gentamicin

A

Aminoglycoside antibiotics

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10
Q

gentamicin

A

Bacterial 30s ribosomal subunit

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11
Q

how does gentamicin work against anaerobes

A

it dosent - requires oxygen

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12
Q

gentamicin important side effects

A

Nephrotoxicity
Ototoxicity
Antibiotic-associated diarrhoea/colitis

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13
Q

vancomycin drug class

A

Glycopeptide antibiotics

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14
Q

vancomycin target

A

NAMA and NAG peptides

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15
Q

vancomycin moa

A

irreversibly block the elongation of peptidoglycan chains by preventing the incorporation of NAMA and NAG peptide subunits

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16
Q

vancomycin bad side effects

A

Nephrotoxicity
Ototoxicity
Blood disorders
Severe hypotension, anaphylactoid reaction on rapid infusion

17
Q

Benzylpenicillin drug class

A

Transpeptidase inhibitor

18
Q

Benzylpenicillin also known as

A

Penicillin G

19
Q

Benzylpenicillin binds to

A

penicillin binding proteins

20
Q

Benzylpenicillin inhibits

A

call wall synthesis

21
Q

good thing about Benzylpenicillin

A

stable against hydrolysis by a variety of beta-lactamases