Cardiac A&P Flashcards
(heart’s anatomical location) ~⅔ heart’s mass:
Bottom of heart aka:
Top of heart aka:
Great vessels:
Aorta diameter:
= L of midline w/ remainder to right
= apex: just above diaphragm, left of midline 5th rib
= Top of heart/base: ~2nd rib.
= connect to the heart through the base.
= ~2 inch
Heart’s 3 tissue layers:
= Endocardium, myocardium, & pericardium.
Endocardium:
= Innermost layer, Lines heart chambers & is in contact w/ blood.
Myocardium:
= Thick middle layer, Resembles skeletal muscle but has electrical properties like smooth muscle, Conducts electrical impulses for heart contraction.
Diastole:
Systole:
= 1st phase, ventricles fills w/ blood, hold 100mLs & pumps 50-70mLs
= “squeeze” 2nd phase, period of cycle myocardium is contracting
!!Poiseuille’s law:
Example:
= vessel w/ relative radius of 1 would transport 1mL per min at BP difference of 100mmHg. Keep pressure constant
= Less blood = vaso-press
Ejection Fraction (EF):
<45% usually indicates:
<30%:
= Ratio of blood pumped from the ventricle to the amount remaining @ the end of diastole/ %of blood pumped out from ventricle (60-70%)
=<45% usually indicates in or going to CHF
=<30% in CHF & chronic cardiac crip on oxy
Preload:
= pressure (volume) w/in the ventricles at the end of diastole & Also commonly called the end diastolic volume (frank starlings law)
Afterload:
= resistance against which the heart must pump against afterload become increased w/ increased ventricular workload
Systemic vascular resistance:
Nitro dynamics:
= how dilated arteries are
= decreases afterload pressure > decreases workload & O2 demand
Contractility:
= ability of CM. cells to contract, or shorten (Actin Myosin)
Stroke volume:
3 factors that affect stroke volume:
= amount of blood ejected by heart in 1 contraction, varies 60-100mLs w/ average 70mL
= preload, afterload, & contractility
Fastest way to effect preload:
= IV bolus Afterload affect vaso-med
Contractilititly factors electrolyte & receptor:
= Calcium & +Beta1 effects
Cardiac output formula:
= SV x HR
(Electrolytes role on heart) NA:
Ca:
K:
= depolarizing myocardium
= depolarization & majority myocardial contractile
= influences repolarizations
(3 internodal pathways) 1:
2:
3:
= SA node to Bachmann’s bundles left atrium
= AV junction to AV node,
= Junction AV node, Sinus SA node
Heart’s Endocrine hormones’:
ANP:
BNP:
= store & secretes 2 hormones released when somewhere in heart fail
= Atrial Natriuretic Peptide: made, stored, & released by atrial-M cells response to atrial distension & Sympathetic stim (counter RAAS & lessen afterload pressure)
= Brain Natriuretic peptide: secreted by ventricles response to stress to excessive stretching of myocytes & Counter RAAS
Tunica intima:
Tunica media:
Tunica adventitia/externa:
Lumen:
= inside layer/ tissue of heart
= middle layer/muscle of heart
= external layer of heart
= where blood flows throughs
!!Starling’s Law of heart:
= states that the more the myocardium is stretched, up to a certain amount, the more forceful the subsequent contraction will be
Chrontropy:
Inotropy:
Dromotropy:
= HR, + tropic +HR vice versa
= Contraction force
= Speed of impulse transmission, usually goes w/ Inotropy
(only in heart) Intercalated discs:
Discs speed Vs standard cell membrane:
Syncytium:
= Special tissue bands inserted between myocardial cells that increase the rate(400x) in which AP is spread from cell-cell thus Syncytium
= 400x faster than standard cell membrane drom/Inotropy
= Group of cardiac cells physiologically function as a unit, “working together in sync” “top in syncytium to bottom”
Cardiac depolarization:
RP of Ac:
RP of Cc:
Phases 0-4 of Cc:
= reversal charges of cell membrane inside becomes + & outside -,
= -60 slow Na & fast Ca -40
= -90 Na & -85 gap Junctions fast Na influxes
= 0 depolar, 1 early repolar, 2 plateau + for +, 3 K pumps, 4 refractory
Side of heart has most myocardium:
Epicardium makes what & how:
Pericardium holds what, w/ what color & Fn.:
= L side of heart (muscle)
= folds over self to make pericardium
= holds 25-50mLs straw color fluid to reduce friction, 150mL = heart can squeeze,
Pectinate ”comb” muscles L. & Fn:
Chordae Tendineae L. & Fn:
= @ Atriums’ to contract for Mitral & Tricuspid valves
= heart tendons connect to Papillary-M.s, down to open atria valves
Foramen Ovale:
Pulmonary stenosis:
= hole in the atrial septum that is part of the fetal blood circulation
= pulmonic valve/arteries rigid
(Heart’s Physiology) Diastole) R-side:
L-side:
= Atrium’s tricuspid valve opens filling ventricle & Pulmonic-V closed
= L atrium’s Bicuspid valve opens filling & streching ventricle & Aortic-V closed
1st & 2nd most common heart defect:
ASD Atrial Septum Defect:
VSD Ventricle Septum Defect:
= ASD atrial septum defect then VSD ventricle septum defect
= hole in atriums’ septum; when breaths & closes, CAUSES L-R SHUNT, overloads right side decreases BP
= hole in ventricle’s septum L→R shunt, R-side balloons > hypertrophic