Carbohydrates 3 Flashcards
Define glycolysis.
Complex series of chemical reactions, not requiring oxygen, that splits glucose, glycogen or other cells into pyruvate.
What cell needs glycolysis for energy?
Red blood cells as they lack mitochondria.
Step 1: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Glucose to Glucose-6-Phosphate
Hexokinase(glucokinase)
-1ATP
Irreversible
Step 2: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Glucose-6-Phosphate to Fructose-6-Phosphate
Phosphohexose isomerase
N/a
Reversible
Step 3: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Fructose-6-Phosphate to Fructose-1,6 -bisphosphate
Phosphofructokinase 1
-1ATP
Reversible (but first committed step)
Step 4: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Fructose- 1,6 -bisphosphate to Dihydroxyacetone phosphate and glyceraldehyde 3-phosphate
Aldolase
N/A
Reversible
Step 5: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Dihydroxyacetone phosphate to glyceraldehyde 3-phosphate
Triose phosphate isomerase
N/A
Reversible
Step 6: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Glyceraldehyde 3-phosphate and Pi to 1,3 -bisphosphoglycerate
Glyceraldehyde 3-phosphate dehydrogenase
1 NADH
Reversible
Step 7: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
1,3 -bisphosphoglycerate to 3-phosphoglycerate and ATP
Phosphoglycerate kinase
N/A
Reversible
Step 8: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
3-phosphoglycerate to 2-phosphoglycerate
Phosphoglycerate mutase
N/A
Reversible
Step 9: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
2-phosphoglycerate - phosphoenolpyruvate
Enolase
H20
Reversible
Step 10: a. Making, b. Catalyst, c. Energy production, D. Reversible/Irreversible
Phosphoenolpyruvate to Pyruvate and ATP
Pyruvate kinase
1ATP
Irreversible
NAD+ needs to be regenerated but what can it be made from?
The vitamin niacin.
What 3 things can happen to pyruvate?
Pyruvate -> ethanol + CO2
Pyruvate -> lactate
Pyruvate -> Acetyl CoA -> CO2 + H2O