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HSCI 180 > Cannabis > Flashcards

Cannabis Flashcards

1
Q

why is marijuana classified separately?

A

effects are varied and complex

  • sedation
  • pain relief
  • hallucinations
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2
Q

what are three species of cannabis?

A

Cannabis sativa

  • originated: asia
  • for fibre: hemp rope
  • lanky plant 18ft

Cannabis indica

  • psychoactive resin
  • 2 to 3 ft high

Cannabis ruderalis
-Russia

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3
Q

what is the primary psychoactive agent in cannabis?

A

THC (delta-9-tetra…)

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4
Q

where is THC concentrated in?

A

Resin (flowering tops)

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5
Q

what is Charas?

A

Hashish

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6
Q

what is ganja?

A

sinsemilla “without seeds”

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7
Q

what is Bhang?

A

powder that can mixed into drinks
-rare in Canada
-red oil cannabis
less than 1%

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8
Q

what is Hashish?

A

pure resin

3-8% THC (maybe up to 20%)

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9
Q

how to efficiently produce hashish?

A

boiling plants in alcohol and evaporating liquid down to thick, dark oil
more than 50% THC

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10
Q

what is sinsemilla

A

dried flowering tops of plants with female plants
-why female? females dont put energy into seed production, thus increasing potency
7-12%

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11
Q

what is the earliest mention of cannabis?

A

Chinese pharmacy 2737 BC

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12
Q

how did the Muslim world use cannabis?

A

socially by 1000AD

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13
Q

what is Hashishiyya?

A

religious cult that carried out political murders

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14
Q

who is the primary supplier for hash products to Canada?

A

Jamaica

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15
Q

what is the average age for initiation into cannabis?

A

15-24

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16
Q

The following is cultivated primarily for its fibres, from which hemp is made:

A

Cannabis sativa.

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17
Q

____ is a preparation of potent marijuana.

A

Sinsemilla

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18
Q

Complete elimination of one dose of THC and its metabolites may take:

A

2 to 3 weeks.

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19
Q

The endogenous substance found in the brain with marijuana-like effects is:

A

anandamide

20
Q

One consistent physiological effect of THC is:

A

increased heart rate.

21
Q

Which of the following effects of marijuana is reliably seen in both infrequent and regular marijuana smokers?

A

slowed cognitive processing

22
Q

Dronabinol (Marinol) has been approved for use:

A

as an antiemetic in conjunction with cancer chemotherapy.

in improving appetite in patients suffering from anorexia and AIDS.

23
Q

One behavioural problem associated with marijuana use is:

A

panic reactions.

24
Q

Sativex is marketed in Canada as a treatment for dealing with neuropathic pain associated with:

A

MS

25
Q

when was THC isolated?

A

1964

26
Q

how is smoked marijuana absorbed?

A

rapidly by blood and travels to brain and then rest of the body

  • 30min
  • peak effects within 5-10 minutes
27
Q

how is oral THC absorbed?

A

more slowly and the liver transforms it

  • less THC reaches brain
  • peak effects within 90 minutes
28
Q

after one week how much THC might remain?

A

25-30%

29
Q

what is the endogenous substance isolated from brain tissue?

A

anadamide

30
Q

what receptors does THC bind to?

A

CB1. CB2

31
Q

where are CB1 receptors primarily found?

A

brain

  • basal ganglia (movement)
  • cerebellum (fine body movement)
  • hippocampus (memory)
  • cerebral cortex (higher cognitive function_
  • nucleus accumbens (reward)
32
Q

where are CB1 receptors primarily found?

A

immune cells

33
Q

what are some cardiovascular effects?

A

increased heart rate

34
Q

what are some pulmonary effects?

A

bronchodilation - after acute exposure

35
Q

Dronabinol (Marinol)

A

oral form treatement for severe nausea, vomiting associated with cancer chemo, and AIDS related anorexia

36
Q

Sativex

A

buccal spray for neuropathy for MS,

analgesic for cancer patient

37
Q

Nabilone

A

synthetic cannabinoid with antiemetic properties (treat vomiting)

38
Q

what plays and important role in the modulation of pain

A

endocannbinoid system

  • supraspinnal
  • spinal
  • peripheral
39
Q

is there a DSM-5 listing for cannabis withdrawal?/

A

no

40
Q

acute physiological effects

A

increased heart rate

41
Q

chronic lung exposure

A

no evidence causes lung cancer

42
Q

toxicity potential

A

panic

feat of loss of control and fear that things wont return to normal

43
Q

reproductive effects

A

diminish sperm count and reduces testosterone levels in men

44
Q

amotivational syndrome true?

A

no, there is no support tha exhbit diminished motivation

45
Q

reefer madness

A

psychosis
but NO evidence that marijuana can increase likelihood of psychotic episodes. Users typically use marijuana in conjunction with other psychoactive drugs

46
Q

cannabidiol

A

produces anxiolytic and antipsychotic effects rather than psychoactive effects

HSCI 180 (8 decks)

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