Canine Viruses Flashcards
Midterm
What kind of virus is rabies? Host?
RNA, enveloped, intracytoplasmatic inclusion bodies, wide range of hosts (mammals)
What are the intracytoplasmatic inclusion bodies called of rabies?
negri bodies
What species get the “furious” form of rabies?
dogs, cats, horses, wild animals
What species get the “dumb” rabies?
cattle and lab animals
How does the virus move from CNS to other organs?
centrifugally (outwards)
What diagnosis technique is NOT useful for rabies?
serology - fatal before antibodies show up
What kind of rabies vaccine is used in prophylactic injections?
inactivated
What are the essential components of post exposure prophylaxis for rabies?
local treatment of wounds and active and passive immunization
What family is canine distemper virus?
Paramyxoviridae
What are the characteristics of the canine distemper virus?
SS RNA, enveloped, forms syncytiums and intracytoplasmatic and intranuclear inclusion bodies
What tissues does canine distemper affect?
pantropic (many tissues) - lymphoid, epithelium, nervous
How is canine distemper transmitted?
direct contact - droplet, aerosols
When is canine distemper shed from the host?
in all secretions from 5th day of infection then for many weeks
What family does infectious canine hepatitis virus belong to?
adenoviridae
What are the characteristics of infectious canine hepatitis?
DNA, naked, intranuclear inclusion bodies
What are the clinical signs of canine hepatitis virus?
asymptomatic or present as undifferentiated respiratory disease
What happens in peracute canine hepatitis?
death in 4 hours, no signs
What happens in acute canine hepatitis?
may be fatal, mild disease, fever, etc
What abnormality happens in natural canine hepatitis infection or a week post live-attenuated vaccination with canine hepatitis?
blue eye - no sequlae
What form of canine hepatitis do we vaccinate against?
CAV-2, crossprotection (because CAV-1 gives corneal edema)
What are the characteristics of canine parvovirus?
DNA, naked, intranuclear inclusion bodies
What are the 3 age-related disease syndromes of canine parvo?
Generalized neonatal - rare
myocarditis syndrome - 4 to 8 week pups, sudden death
leukopenia/enteritis syndrome - pups 8-12 weeks
What are the characteristics of canine coronavirus?
RNA, enveloped
What kind of disease does corona virus produce?
mild gastroenteritis, doesnt require specific diagnosis
What bacteria are involved in kennel cough?
bordetella bronchiseptica, pseudomonas, E. coli, klebsiella, pasteurella, strep, mycoplasma
What viruses can be involved in kennel cough?
canine hepatitis, parainfluenza, corona, reovirus, herpes, influenza
What family is canine influenza virus in?
orthomyxoviridae
What are the characteristics of the canine influenza virus?
RNA, SEGMENTED, enveloped
What diagnostic test can NOT be used for canine influenza?
antigen ELISA
What family is the canine parainfluenza virus?
paramyxoviridae
What are the characteristics of canine parainfluenza?
RNA, enveloped
What family is hemorrhagic disease of pups in?
herpesviridae
What are the characteristics of hemorrhagic disease? (herpes)
DNA, enveloped, intranuclear inclusion bodies
What kind of shedding does hemorrhagic disease have? (herpes)
latent, recrudescent and intermittent or continous
How is hemorrhagic disease of pups transmitted? (herpes)
sexually transmitted, passed to puppies
What problems can hemorrhagic disease (herpes) cause?
abortion, stillbirths, infertility, kennel cough
What secretions shed the hemorrhagic disease (herpes) virus?
pile, vaginal secretions, discharge from nose. also raised sores on repro parts
What allows CHV to spread to the rest of the body in a puppy?
low body temperature
What can be a sequlae in CHV in puppies that survive?
neurologic disease
What are the clinical signs of CHV?
Vasculitis - hemorrhage
Bruising of belly
eye lesions - keratitis, uveitis, optic neuritis, retinitis, retinal dysplasia
high mortality rate
What are characteristics of canine papillomatosis virus?
DNA, naked, circular
Where are lesions seen in canine papilloma virus?
cutaneous and mucous membranes
Where are papillomas seen in young dogs? all ages?
young - oral, ocular, genital
all ages - cutaneous
What are the 3 systemic canine viruses?
Distemper
Infectious Canine Hepatitis
Parvo
What are the 4 canine respiratory viruses?
Canine tracheobronchitis
Canine influenza
Parainfluenza 2
Canine adenovirus 2
What is the only canine virus that affects reproductive system?
hemorrhagic disease of puppies
What is the only canine virus that affects JUST the GI tract?
canine coronavirus
What is the “gold standard” for diagnosing rabies infection?
DFA (direct flourescent antibody test)
What is the most DEFINITIVE diagnostic test for rabies?
virus cultivation from saliva and infected tissue
What are the 4 canine DNA viruses?
Adenovirus (hepatitis)
Parvo
Herpes (hemorrhagic dz of pups)
Papova
What are the 3 canine viruses that are NOT enveloped?
Canine hepatitis
Parvo
pailloma
which virus family can a autovaccine be used?
papovaviridae
Which virus does not grow in cell culture?
papovaviridae
Which herpes virus is not species specific?
pseudorabies
Which viruses do not leave intracellular inclusion bodies?
papova corona retro viruses reoviridae (rota) orthomyxo
Which virus exits by lysis?
caliciviridae
Which virus family is enveloped but moderrately resistant in environment?
corona
