Cancer Flashcards
Cellular growth, not responding to regulation processes
neoplasm
Dysplasia leads to
neoplasia
Generally the neoplasms are due to a
mutation
Characteristics of cancer
rapid
uncontrolled proliferation
loss of differentiation
Is the formation of cancer
carcinogenesis
Stages of carcinogenesis
- Initiation
- Promotion
- Progression
Stage of carcinogenesis that involve the exposure of the cells to environmental events such as DNA mutation, chemical, viruses or radiation
initiation
Stage of carcinogenesis where the mutated cells are exposed to hormones and promote the growth
promotion
Stage of carcinogenesis where the tumor invades and metastasizes
progression
In the stage of progression in the carcinogenesis the damage is
irreversible
Protein products that stimulate the cell growth and division
oncogenes
Is the positive regulation of cell cycle
oncogenes
What is an proto-oncogene?
precursor of oncogene
Is the negative regulation of cell cycle
tumor suppressor gene
Protein products stop cell cycle and promote apoptosis
tumor suppressor gene