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Immunology Final > Cancer > Flashcards

Cancer Flashcards

1
Q

What is an oncogene

A

cancer causing gene

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2
Q

are solid tumors blood cell or non blood cell

A

non blood cell

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3
Q

what are the 2 types of solid tumors

A

carcinoma and sarcoma

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4
Q

what are the 2 types of blood cell cancer

A

Leukemia and Lymphoma

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5
Q

what is the other way to classify cancer

A

spontaneous or virus-associated

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6
Q

which is more common: spontaneous or virus-associated

A

spontaneous

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7
Q

how do you get a spontaneous CA

A

exposure over time

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8
Q

what is virus-associated CA

A

Infxn linked to CA

accelerate the progression of CA

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9
Q

what are 5 examples of DNA and RNA tumor viruses

A
  1. HPV (an sti)
  2. Hep B (liver CA)
  3. EBV (burkitts lymphoma)
  4. HHV (kaposis sarcoma)
  5. HTLV (leukemia)
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10
Q

what causes spontaneous CA

A

chemicals, radiation, diet, metabolism

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11
Q

can you recover and decrease your risk of Lung CA if you stop smoking

A

yes

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12
Q

is CA usually inherited

A

no

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13
Q

is CA from a single even or multiple events

A

multiple | progression

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14
Q

what are some characteristics of CA

A
  • proliferate and invade tissue
  • mets to other areas
  • evade apoptosis
  • turns on/off genes
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15
Q

is CA rare of common at the cellular level

A

RARE

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16
Q

does CA respond to inhibitory factors

A

NO

17
Q

what are the properties of CA cells

A
  1. loss of cell signaling and cell cycle
  2. anchorage independent growth
  3. grow in the absense of stim growth signals
  4. seem immortal
18
Q

what does Tumor suppressor genes do

A

encode proteins that restrain cell growth (puts the brake on cell cycle)

19
Q

what does oncogenes do

A

encode proteins that promote loss of growth control and the conversion of a cell to the malignant state

20
Q

does TSG act dominantly or recessively

A

recessively

21
Q

does oncogenes act recessively or dominantly

A

dominatly

22
Q

what does Proto-oncogenes do

A

encode proteins that have various functions in the cells normal activities

Immunology Final (8 decks)

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