Cancer Flashcards
what is the causes of cancer
Cancer results from genetic changes that affect the cell cycle.
This is done by mutations that affect cell growth and division
what are the three types of cancer:
A. Torrents
B. Carcinomas
C. Sarcomas
D. Leukaemia and lymphomas
B, C, D
what does Benign mean
do not spread from their side of the origin, but can crowd out the surrounding cells e.g
Brain Tumours
What does Malignant mean
can spread from the original site and cause and caused secondary tumours
what is Metastasis
caused from Malignant tumours by invading other tissues and kill organisms and is the secondary tumour level
name the two major classes of cancer
tumour suppressor genes
oncogenes
what is a tumour suppressor genes
encoding proteins which inhibit cell proliferation, which signals proteins and others
RECESSIVE mutations
what is oncogenes
encoding proteins which stimulate cell proliferation, which signals proteins and others
DOMINANT mutations
describe how a ras protein is involved in cancer
is found in about a quarter of all human tumours, it acts as a signalling protein to stimulate cell proliferation
only activates which there is a correct cell surface receptor binds to a growth factor (G protein)
pathway is perinatally switched on