Calcium Imbalance Flashcards

1
Q

th e3 fractions of calcium are

A

iCa (50%), complexed/chelated Ca (10%), protein bound Ca (40%)

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2
Q

T/F: animals get their vitamin D from sunlight

A

FALSE ITS FROM FORTIFIED FOODS

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3
Q
When calcium levels are too high, thyroid releases \_\_\_\_\_\_.
A) PTH
B) Vitamin D
C) calcitriol
D) calcitonin
A

D - calcitonin

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4
Q
When Ca levels are too low, parathyroid gland releases:
A) PTH
B) vitamin D
C) calcitriol
D) calcitonin
A

A - PTH

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5
Q

3 important tissues that PTH and calcitonin act on

A

bone, intestines, kidneys

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6
Q

T/F: when Ca is high, the thyroid releases calcitonin resulting in increased Ca release from bones

A

False - increased calcitonin increases Ca deposition in bones, not release

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7
Q

T/F: PTH increases osteoclast activity

A

true

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8
Q

Clinical signs of hypercalcemia

A

PU/PD - nephrogenic diabetes insipidus, kidney can’t respond to ADH
weakness, lethargy, inappetence, v/d, reduced excitability of nervous tissue

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9
Q

DDx of hypercalcemia (there are 8)

A
HARDIONS
hyperparathyroidism
addison's 
renal failure
hypervitaminosis D
idiopathic hypercalcemia of cats
osteolysis
neoplasia
spurious
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10
Q

What happens if Ca and P >70?

A

dystrophic mineralization

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11
Q

Describe relationship between Ca and P

A

as one goes up the other goes down (in normal conditions) - inverse relationship

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12
Q

2 causes of hypercalcemia due to malignancy

A

lymphoma

apocrine gland carcinoma (anal glands)

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13
Q

2 etiologies of hypocalcemia

A

Primary hypoparathyroidism and eclampsia

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14
Q

What is eclampsia?

A

milk fever, puerperal Tetanu
acute, life threatening
excessive loss of Ca in milk
small breed dogs

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15
Q

Ideal for diagnosis of hypocalcemia?

A

serum ionized calcium

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16
Q

T/F: hypoPTH results in hypocalcemia and hypophosphatemia

A

False, phosphorus will be high with hypoPTH

17
Q

What is emergency treatment of hypocalcemia

A

10% calcium gluconate IV slow over 10-30 mins, monitor w/ ECG
continue w. supportive IV or SQ Ca therapy
monitor temp

18
Q

Tx for eclampsia?

A

wean pups, place bitch on oral Ca supplements

19
Q

What is another name for man made active Vitamin D supplement 1,25-dihidroxycholecalciferol?

A

Calcitriol

20
Q

What is Calciferol?

A

ergocalciferol hydroxylated to 25-hydroxyvitamin D in liver, then activated to 1,25-dihydroxyvitamin D, primary active form of drug