Calcium/Hard Tissue Flashcards
Enamel matrix is ____ and is ___ HA
amelogenin; 90%
dentin matrix is ____ and is ___ HA
collagen; 67%
things that promote resorption
PTH PTH-related protein Prostaglandin IL-1, IL-6, and TNF prolactin corticosteroids Vitamin D
things that inhibit resorption
calcium estrogens calcitonin tumor growth factor- beta IL-17
how Ca is distributed in serum
50% ionized Ca- free Ca- biologically active
40% protein bound- bound to albumin- biologically inactive, not excreted
10% bound to phosphate, bicarbonate, or citrate
____ is the primary regulator of Ca levels
PTH
PTH triggers an increase in ____; production stimulated by ____
serum Ca; low plasma Ca
32 amino acid protein produced by C-cells that inhibits bone resorption
calcitonin
Ca is absorbed in the ____; active transport regulated by ____; transport based on relative ____
small intestine; vitamin D; serum/gut levels