Caddena de transporte de electrones Flashcards

1
Q

Cadena transportadora de electrones

A

Metabolismo terciario
Transforma potencual redox en ATP
Moviliza electrones alamcenados en NAD y FAD
En membrana interna mitocondrial

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2
Q

Complejo 1

A

NADH Q reductasa
Electrones de NADH a Coenzima Q
Bombea 4 protones
Rotenona inhibe

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3
Q

Complejo 2

A

Succinato Q reductasa
Electrones de FADH2 (vienen de succinato)a Coenzima Q
Carboxina inhibe

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4
Q

Complejo 3

A

Citocromo reductasa/b-c1
Electrones de Coenzima Q a citocromo
Bombea 4 protones
Antimicina inhibe

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5
Q

Complejo 4

A

Citocromo oxidasa
Electrones de citocromo a oxígeno
Bombea 2 protones
Cianuro inhibe

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6
Q

Bombeo de protones

A

De adentro hacia afuera de mitocondria
Forma potencial eléctrico (+ afuera y - adentro)
Forma potencual químico (ácido afuera y basico adentro)

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7
Q

Fuerza protón motriz

A

Energía que permite generar ATP
Formado de potencial electrico y quimico

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8
Q

ATP sintasa

A

Forma ATP
Enzima integrada a membrana de la mitocondria
F0: Membrana interna y Átomos de hidrogeno regresan a matriz
F1: En matriz y Gira
Sintetiza ATP
Oligomicina inhibe

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9
Q

Balance energetico de cadena de transporte de electrones

A

30 o 32 ATP

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10
Q

Desacopladores

A

Compuestos natural o sintetico que crea poros en membrana interna de mitocondir
Protones salen por poros, no se forma energía, se forma calor
* 2-4-dinitrofenol
* Piroxina
* Termogenina

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11
Q

2-4-dinitrofenol

A

DNP
Desacoplador artificial

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12
Q

Piroxina

A

Regulación hormonal
Crea calor

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13
Q

Termogenina

A

Tejido adiposo pardo
Abundante en bebés

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