Ca2+ antagonists

Question 1

dihydropyridine

Answer 1

used in hypertension and angina
vasodilators dont act on the heart

Question 2

rate limiting calcium antagonists

Answer 2

used in hypertension, angina and supraventricular arrythmias

Question 3

mechanism of action

Answer 3

interfere with the inward displacement of calcium ions through the slow channels of active cell membranes

Question 4

contraindications and cautions

Answer 4

• CBBS, especially rate limiting ones should not be administered to patients being treated with a beta blocker
• beta blockers depress cardiac electrical and mechanical activity and therefore the addition of a CCB augments the effects of the beta blockade

Question 5

side effects

Answer 5

• Dizziness
• Flushing
• Headache
• Nausea
• Dihydropydines - ankle oedema

Question 6

administration

Answer 6

PO