Angiotensin receptor blockers Flashcards
1
Q
exaamples
A
losartan
valsartan
2
Q
main indications
A
hypertension
post MI
heart failure when ACEi is not tolerated
3
Q
mechanism of action
A
- Competitively inhibits the binding of angiotensin II to AT1 in many tissues including vascular smooth muscle and the adrenal glands
- Causes vasodilation and blockage of aldosterone release
4
Q
contraindications and cautions
A
Contraindicated in pregnancy/planning to become pregnant
5
Q
adverse effects
A
dizziness
hyperkalaemia
localised angioedema
6
Q
administration
A
PO or IV
