Aspirin Flashcards
1
Q
main indications
A
- main antiplatelet agent
- ACS
- ischaemic stroke
- thromboprophylaxis in patients at high cardiovascular disease
2
Q
mechanism of action
A
irreversibly block cyclooxygenase in platelets - inhibits TXA2 synthesis and also inhibits production of antithrombotic prostaglandin I2
3
Q
contraindications and cautions
A
avoid in active peptic ulcerations and bleeding disorders
4
Q
adverse effects
A
GI bleeding and ulceration
5
Q
administration
A
PO