Bunyaviridales Flashcards
Why bunya?
Bunyamwera = place in Uganda
Families (12)
- Peribunyaviridae
- Phenuiviridae
- Nairoviridae
- Hantaviridae
Morphology
-ssRNA genome, segmented, helical capsid, enveloped, big
Resistance
Weak (except Hantaviridae)
Replication
Baltimore V - viral transcriptase
type of viruses
arboviruses - mosquito of tick transmission
except Hantavirus, who survives in the environment
Zoonoses?
Yes
antigenic properties
relatively good antigens, cross-reaction within genera
Diagnosis
- Direct: isolation, IF, EM
- Indirect: NV, HAI
Peribunyaviridae - Orthobunyavirus genus:
Akabane disease
- ruminants: congenital arthrogryptosis, hydrencephaly + abortion & foetus development problems
- mosquito-transmitted (Far-East, Asia, Israel)
Peribunyaviridae - Orthobunyavirus genus:
Schmallenberg virus
- ruminants: febrile illness, congenital disorders + abortion & foetal development problems
- transmitted by medges (Europe)
Peribunyaviridae - Orthobunyavirus genus:
La Crosse virus, Tahyna virus, Inkoo virus & California encephalitis virus
human: fever, rash, encephalitis
Phenuviridae - Phlebovirus genus:
why phlebo?
Phlobotomidae = Sandfly
Phenuviridae - Phlebovirus genus:
Rift Valley fever
- sheep, cattle, human: abortion, fever, bloody diarrhea, icterus, high mortality
- mosquito-transmitted (Africa)
Nairoviridae - Orthonairovirus genus
why nairo?
nairo - Nairobi
Nairoviridae - Orthonairovirus genus
Nairobi sheep fever
- sheep, goat, human: fever, gastroenteritis, abortion
- tick-transmitted (Africa, Asia)
Nairoviridae - Orthonairovirus genus
Crimean-Congo haemorrhagig fever
- humans (+ ruminants, infectious source): hemorrhage, rash, nephritis
- tick-transmitted (Asia, Middle-East, Africa, especially Turkey)
Hantaviridae - Orthohantavirus genus:
Why hanta?
Hantaan = Korean region
Hantaviridae - Orthohantavirus genus:
Hantaan hemorrhagic fever with renal syndrome
-human: fever, nephritis, high lethality
-reservoir: rodents (rats, deer mouse, cotton mouse, vole, etc.)
(Far-East, Europe, USA)
