Bunyaviridales Flashcards

1
Q

Why bunya?

A

Bunyamwera = place in Uganda

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2
Q

Families (12)

A
  • Peribunyaviridae
  • Phenuiviridae
  • Nairoviridae
  • Hantaviridae
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3
Q

Morphology

A

-ssRNA genome, segmented, helical capsid, enveloped, big

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4
Q

Resistance

A

Weak (except Hantaviridae)

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5
Q

Replication

A

Baltimore V - viral transcriptase

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6
Q

type of viruses

A

arboviruses - mosquito of tick transmission

except Hantavirus, who survives in the environment

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7
Q

Zoonoses?

A

Yes

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8
Q

antigenic properties

A

relatively good antigens, cross-reaction within genera

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9
Q

Diagnosis

A
  • Direct: isolation, IF, EM

- Indirect: NV, HAI

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10
Q

Peribunyaviridae - Orthobunyavirus genus:

Akabane disease

A
  • ruminants: congenital arthrogryptosis, hydrencephaly + abortion & foetus development problems
  • mosquito-transmitted (Far-East, Asia, Israel)
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11
Q

Peribunyaviridae - Orthobunyavirus genus:

Schmallenberg virus

A
  • ruminants: febrile illness, congenital disorders + abortion & foetal development problems
  • transmitted by medges (Europe)
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12
Q

Peribunyaviridae - Orthobunyavirus genus:

La Crosse virus, Tahyna virus, Inkoo virus & California encephalitis virus

A

human: fever, rash, encephalitis

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13
Q

Phenuviridae - Phlebovirus genus:

why phlebo?

A

Phlobotomidae = Sandfly

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14
Q

Phenuviridae - Phlebovirus genus:

Rift Valley fever

A
  • sheep, cattle, human: abortion, fever, bloody diarrhea, icterus, high mortality
  • mosquito-transmitted (Africa)
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15
Q

Nairoviridae - Orthonairovirus genus

why nairo?

A

nairo - Nairobi

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16
Q

Nairoviridae - Orthonairovirus genus

Nairobi sheep fever

A
  • sheep, goat, human: fever, gastroenteritis, abortion

- tick-transmitted (Africa, Asia)

17
Q

Nairoviridae - Orthonairovirus genus

Crimean-Congo haemorrhagig fever

A
  • humans (+ ruminants, infectious source): hemorrhage, rash, nephritis
  • tick-transmitted (Asia, Middle-East, Africa, especially Turkey)
18
Q

Hantaviridae - Orthohantavirus genus:

Why hanta?

A

Hantaan = Korean region

19
Q

Hantaviridae - Orthohantavirus genus:

Hantaan hemorrhagic fever with renal syndrome

A

-human: fever, nephritis, high lethality
-reservoir: rodents (rats, deer mouse, cotton mouse, vole, etc.)
(Far-East, Europe, USA)