Bugs, parasites, infections Flashcards
What are possible reactions to arthropod bites?
excoriated pruritic papules, papular urticaria, pemphigoid vesicles and bullae, pseudolymphomatous nodules, anaphylaxis, secondary infections
What are some diseases transmitted by fleas?
Rickettsia typhi, yersinia pestis
What are some diseases transmitted by ticks?
Lyme disease, rocky mountain spotted fever, ehrlichiosis, anaplasmosis, tularemia
What is the typical presentation of bedbug bites?
Erythematous pruritic nodules that often appear overnight in a linear or grouped arrangement (breakfast, lunch, and dinner bites)
Where are bedbugs found?
Crevices of floors and walls, beddings, furniture (can survive for a long time without feeding)
What is the vector for lyme disease?
Ixodes scapularis (deer tick)
What are the three stages of lyme borreliosis?
Stage 1: localized
Stage 2: disseminated
Stage 3: persistent infection (months or years later)
What is the classic presentation of lyme disease?
Erythema migrans with an initial erythematous macule/papule that enlarges within days to form an expanding annular lesion with a distinct red border and partially clearing center (bull’s eye)
What organism causes scabies?
The mite sarcoptes scabiei
How are scabies transmitted?
Skin to skin contact with another person with the parasitic infection
What is the life cycle of the organism that causes scabies?
The female scabies mite burrows into the top layers of skin where she lays up to 3 eggs per day for one to two months
What is the clinical presentation of scabies in immunocompetent patients?
Pruritic papules, usually somewhat scaly or crusted, preferentially distributed in “warm” areas of the body (axillae, groin, ankles, etc)
What is the clinical presentation of scabies in immunocompromised patients?
“crusted” or norwegian scabies with thick scaly plaques over most of the body
How is scabies diagnosed?
“scabies prep” - microscopic examination of skin scrapings that can reveal mites, eggs, or scybala (mite feces)
What are different causes of pediculosis?
Pediculus humanis var. capitus (head), pediculus humanis var. humanus (body), pthirius pubis
What is the transmission of pediculosis?
Direct contact between individuals or indirect contact with bedding, brushes, or clothing
How is head lice identified?
Nits or organisms in hair
What is the cause of tunga penetrans?
Sand flea infestation, classically along the toenail fold
What is the appearance of lesions in tunga penetrans?
Papule or vesicle with central back dot (from the flea), can have intralesional hemorrhage, eggs/feces/flea organs are extruded when lesions are squeezed
What locations are most likely sites for tunga penetrans lesions?
Feet, especially under toenails, between toes, and plantar aspects of feet
What is the agent that causes cutaneous larva migrans?
Nematode parasites (a variety)
What are the clinical manifestations of cutaneous larva migrans?
Erythematous, serpiginous, papular, or vesicular linear lesions
What is the clinical presentation of myiasis?
A domed nodule that has a central pore through which the posterior end of botfly larva protrudes to respire
A patient complains of itchy finger webs and on examination has scaling between the fingers, a few scaly papules on the wrists, and edematous pink papules and a few nodules on the scrotum. Next step:
a) recommend testing for STDs
b) skin scraping for KOH to evaluate for tinea manuum
c) skin scraping for scabies preparation
d) treatment for psoriasis
c) skin scraping for scabies preparation
scrotal nodules are scabies until proven otherwise
A patient was hiking in upstate New York 2 weeks ago and got many bug bites. One in the groin has not gone away but rather grown into a large annular plaque which she fears is ringworm. On examination she has a 7 cm pink annular nonscaly plaque in the inguinal area. She feels otherwise well. You suspect:
a) bedbug bites from her hotel
b) tinea cruris
c) erythema marginatum
d) erythema migrans
d) erythema migrans
classic presentation of lyme borreliosis
A patient presents with several linearly arranged pruritis edematous excoriated 5 mm papules on both of her legs. These seem to come in crops. It is winter and she has no known exposure to mosquitoes. Her husband may have had a few similar lesions. You recommend:
a) use of DEET when she goes outdoors
b) treatment for shingles
c) professional extermination
d) she should get a new mattress
c) professional extermination
classic description for bedbugs, which requires extermination
What is your diagnosis?
a) tinea versicolor
b) tinea corporis
c) tinea capitis
d) scabies
e) herpesvirus infection
b) tinea corporis
What is the most likely diagnosis?
Tinea corporis
What is the appearance of tinea corporis on KOH prep?
Fungi with hyphae that have septations
What is the most likely diagnosis?
Tinea corporis
What is the most likely diagnosis?
a) tinea versicolor
b) tinea corporis
c) tinea capitus
d) scabies
e) herpesvirus infection
c) tinea capitus
What is the histological presentation of tinea capitus?
Spores within and along hair shaft
What is the leading diagnosis?
Tinea capitus
What is the leading diagnosis?
a) tinea versicolor
b) tinea corporis
c) tinea capitus
d) scabies
e) herpesvirus infection
a) tinea versicolor
What is the appearance of tinea versicolor on histology?
Spaghetti and meatballs (yeast)
What is the most likely diagnosis?
Tinea versicolor
What is the most likely diagnosis?
Herpesvirus infection
What is the most likely diagnosis?
Scabies
What is the most likely diagnosis?
Scabies
What is the most likely etiology of scrotal nodules?
Scabies
What is the most likely diagnosis?
Scabies
What is the most likely diagnosis?
Norwegian scabies (scabies in immunocompromsied patients)
What organism is this? What disease might it transmit?
Louse - epidemic typhus
What disease might this transmit?
Lyme disease (deer tick)
What is the most likely diagnosis?
Lyme disease
What type of organism is this?
Bedbugs
What is the most likely diagnosis?
Bedbugs (breakfast, lunch, and dinner bites)
What is the most likely diagnosis?
Tunga penetrans/tungiasis
What is the most likely diagnosis?
Myiasis
What are the clinical presentations of tinea capitis?
Seborrheic (scaling with minimal inflammation), black dot (hair shaft is brittle and breaks at scalp), kerion (inflammatory, boggy plaque with broken hairs and oozing purulence)
What is the appearance of tinea capitis on Wood’s lamp?
Green fluorescence in hair above level of scalp due to pteridines from infection
What types of infections cause tinea capitis?
Dermatophyte infection (microsporum, trichophyton, epidermophyton species)
How should tinea capitis be evaluated?
With a KOH prep of the hair and/or fungal culture
What is the treatment for tinea capitis?
Oral antimycotic agents and selenium sulfide or ketoconazole shampoo
What is the clinical presentation of tinea corporis?
Dermatophyte infections of glabrous skin, pruritic lesions with central clearing that resemble a ring (“ring worm”), centrifugal spread after 1-3 weeks incubation
What is the clinical presentation of tinea facei?
A form of tinea with facial involvement that excludes beard and moustache areas
What is the treatment for tinea corporis, cruris, facei, manuum, and pedis?
Topical or systemic -azole treatments
What is the most common cause of superficial and systemic candidiasis?
Candida albicans