Approach to Joint Pain Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What types of inflammatory joint pain are often symmetric and polyarticular?

A
  • Rheumatoid Arthritis
  • Systemic Rheumatic Disease
  • Infectious Arthritis
  • Polymyalgia Rheumatica
  • Relapsing seronegative symmetrical synovitis with pitting edema
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2
Q

What types of inflammatory joint pain are often asymmetric and oligoarticular?

A
  • Psoriatic arthritis
  • Enteropathic arthritis of IBD
  • Infectious arthritis from GC, lyme, fungal causes
  • Crystalline arthritis
  • Familial Mediterranean fever
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3
Q

What is the typical location and symmetry of rheumatoid arthritis?

A

Symmetric and polyarticular

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4
Q

What is the typical location and symmetry of psoriatic arthritis?

A

Asymmetric and oligoarticular

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5
Q

What is the typical location and symmetry of enteropathic arthritis?

A

Asymmetric and oligoarticular

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6
Q

What is the typical location and symmetry of infectious arthritis?

A

Could be either symmetric/polyarticular or asymmetric/oligoarticular depending on the source of infection

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7
Q

How long does morning stiffness last in inflammatory vs non-inflammatory joint pain?

A

Inflammatory: > 1 hour

Non-inflammatory: < 30 min

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8
Q

Which type of joint pain (inflammatory or non-inflammatory) improves with activity?

A

Inflammatory (non-inflammatory joint pain is worse with activity)

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9
Q

Which type of joint pain (inflammatory or non-inflammatory) improves with rest?

A

Non-inflammatory (inflammatory joint pain is worse with rest)

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10
Q

Which type of joint pain responds to steroids?

A

Inflammatory (non-inflammatory joint pain often does not respond to steroids)

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11
Q

What are common etiologies of inflammatory joint pain?

A

Rheumatoid arthritis, spondyloarthropathies (ex. psoriatic arthritis, ankylosing spondylitis, etc), and inflammatory arthritis in connective tissue disease

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12
Q

What are common etiologies of non-inflammatory joint pain?

A

Osteoarthritis, fracture/injury, osteonecrosis, amyloidosis, tumor/malignancy

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13
Q

Which condition do the following clinical images relate to?

A

Rheumatoid arthritis

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14
Q

What is an ESR test?

A

An erythrocyte sedimentation rate test that measures how long it takes for red blood cells to sink in a blood sample, indicating the presence or absence of inflammation. A low ESR suggests inflammation.

**can increase with age, be higher in women/patients with ESRD/DM2/pregnancy, be lower in patients with CHF or sickle cell**

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15
Q

What is a CRP test used for?

A

A C-Reactive protein test measures inflammation in the body. Presence of high levels of CRP indicates inflammation.

**More sensitive than ESR, less variable than ESR, affected by age/gender/heart disease/infection/malignancy/obesity/DM2/Smoking**

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16
Q

What diseases is rheumatoid factor associated with?

A

Rheumatoid arthritis, mixed cryo, infections, sarcoid, malignancy, autoimmune connective tissue disease, sometimes healthy people

17
Q

What diseases are anti-cyclic citrullinated peptides (anti-CCP) associated with?

A

Rheumatoid arthritis

18
Q

What diseases are positive ANAs associated with?

A

Autoimmune diseases, sometimes healthy populations

19
Q

What diseases are positive ANCAs associated with?

A

Systemic vasculitis, drug induced

20
Q

Describe group 2 (inflammatory) synovial fluid?

A

Clear to slightly turbid, 200-2000 WBC count, <20% PMNs