BREIF IDEA ON PATHOGENISIS OF DJD

Question 1

Why does degenerative changes in bones usually occur ?

Answer 1

Overuse and excessive pressure on that joint.

Question 2

After wear and tear of a joint what is your bodies first response ?

Answer 2

It is an inflammatory response and an increase in white blood cells in that area after increasing the vascular permeability in that area.

Question 3

How is an inflammatory arthropathy caused by white blood cells ?

Answer 3

Once these white blood cells enter the damaged site, white blood cells can mistakably eat away at healthy cartilage tissue.

Question 4

Can you see an erosive (inflammatory arthropathy) and sclerotic (degenerative) change in the same joint ?

Answer 4

YES,
It can be as a result of healing the inflammatory process you also get degenerative changes in the same joint.

Question 5

Name three basic principles seen in inflammatory arthritis ?

Answer 5

1Affects the Synovium.
2 Uniform joint space narrowing.
3 Erosions of articular bone.

Question 6

What is the difference between an inflammatory arthritis and degenerative arthritis ?

Answer 6

Inflammatory is an inflammatory response in that joint.
Degenerative is wear and tear in that joint.

Question 7

Name four basic principles seen in degenerative arthritis ?

Answer 7

1Irregular joint space narrowing.
2. Wearing down of articular cartilage.
3 Osteophytes. (body tries to fic the degeneration resulting in osteophytes.)
4 Wearing down of articular bone.

Question 8

Name three basic characteristics a metabolic arthritis may have ?

Answer 8

1 Normal joint.
2 Sharply margined erosions.
3 Soft tissue masses.

Question 9

What would help you to differentiate between a metabolic arthritis and a degenerative arthritis ?

Answer 9

Metabolic arthritis will have normal joint spaces and sharply margined erosions. Also soft tissue involvement.