Brain Tumours Flashcards

1
Q

Presentation of brain tumours

A

Focal neurological symptoms, symptoms of raised ICP

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2
Q

Sign of raised ICP in the eyes

A

Papilloedema

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3
Q

Concerning featurs of headache indicating investigation

A

Contant, nocturnal, worse on waking, worse on coughing, straining or bending forward, vomiting

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4
Q

Symptoms of raised ICP

A

Altered mental state, visual field defects, seizures, unilateral ptosis, third and sixth nerve palsies, papilloedema

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5
Q

Common cancers to metastasise to the brain

A

Lung, breast, renal cell carcinoma and melanoma

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6
Q

What are gliomas

A

Tumours of the glial cells in the brain or spinal cord

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7
Q

Three types of gliomas

A

Astrocytoma, oligodendroglioma and ependymoma

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8
Q

What are meningiomas

A

Tumours growing from the meninges in the brain and spinal cord, usually benign

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9
Q

Complications of a pituitary tumour

A

Compression of optic chiasm leading to bitemporal hemianopia. Hormone deficiencies or hormone excess - acromegaly, hyperprolactinaemia, cushings, thyrotoxicosis

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10
Q

What is an acoustic neuroma (vestibular schwannoma)

A

Tumours of schwann cells surrounding the auditory nerve, around the cerebellopontine angle

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11
Q

Symptoms of acoustic neuroma

A

Hearing loss, tinnitus and balance problems, unilateral

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12
Q

Treatment of pituitary tumours

A

Trans-sphenoidal surgery, radiotherapy, bromocriptine to block prolactin secreting tumours and somatostatin analogues to blow growth hormone tumours

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13
Q

What is Broca’s aphasia

A

Problems producing speech, speak with isolated words, abrupt and incoherent sentences

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14
Q

What is Wernickes aphasia

A

No understanding of whats being said, so replies make no sense and often use the same word

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15
Q

Features of temporal lobe pathology

A

Propagnosia and pareidolla

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16
Q

What is retrograde amnesia

A

Memory loss of past events

17
Q

What is anterograde amnesia

A

Memory loss of new events

18
Q

What is somatosensory agnosia

A

Tactile disorder with inabaility to identify object by active touch

19
Q

What is neglect syndrome

A

Unilateral right parietal lobe damage which causes perceptual difficulty on left. Failure to attend to left side. Damage to left parietal lobe does not generate severe right sided hemi-neglect

20
Q

What causes somatosensory agnosia and neglect syndrome

A

Damage to parietal cortex

21
Q

Symptoms of damage to the frontal association cortex

A

Associated with personality changes, ideomotor aprazxia and conceptual/ideational apraxia