Brain flow Flashcards

1
Q

Functional consequences blood flow to brain

A

vital for survival

performance
cognitive function
impairement - dementia, stroke, TBI/concussion

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2
Q

Effects of ageing on the brain

A

decrease size

exercise offset natural age-related decline in brain blood flow
aerobic exercise and brain blood flow positively related

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3
Q

Brain imaging techniques

A

MRI
ASL - arterial spin labelling
transcranial doppler
near-infrared spectroscopy

combination best

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4
Q

Consequences large changes in blood pressure during exercise

A

faint
drop in blood pressure

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5
Q

Cerebral blood flow regulators

A

cerebral autoregulation
cardiac output
blood pressure
metabolism
(para)sympathetic nerve activity

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6
Q

Brain blood flow responsiveness to CO2

A

increase CO2 = increase brain blood flow

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7
Q

Brain blood flow during exercise

A

increase to 65% VO2max
continue to rise as exercise intensity increases

max threshold = hyperventilation = BBF decrease

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8
Q

Dominant regulator BBF

A

PaCO2

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9
Q

Autoregulation due to

A

locally produced factors such as nitric oxide, prostaglandins and adenosine

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10
Q

Sympatholysis

A

local inhibition of sympathetic-induced vasoconstriction

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11
Q

Local increase in nitric oxide conc around arterioles =

A

vasodilation

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12
Q

Where is the greatest resistance to blood flow?

A

arterioles

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13
Q

What is the distribution of cardiac ouput to the heart in the transition from rest to exercise?

A

% cardiac output unchanged
volume blood increases

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