Bone Tissue (2 webinars) Flashcards

1
Q

what makes bone tissue specialized ?

A

it has a hard and calcified (mineralized) extracellular matrix . calcium salts are deposited in ground substance

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2
Q

what is the cell responsible for maintenance of bone ?

A

osteocytes

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3
Q

what are the main functions of the bone?

A

support and protect

provides levers for muscle ( muscle cannot work without bone )

stores calcium phosphorus minerals

red marrow inside bone is site for formation of blood cells (hematopoeisis )

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4
Q

describe the structure of the bone –0——–

A

the outer layer is covered by periostium

the inside is covered in a very thin layer called endostium

in between we will find the cells
osteocytes are present in the middle while the oseoblast are on the peripheral side of the inside of the cell

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5
Q

what is the periosteum ?

A

the outer cover layer of the bone . it is composed of external fibrous layer and inner vascularized layer ( osteoblasts , also known as osteo-progenitor layer )

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6
Q

what cell is responsible for healing fractures in bones?

A

osteo-progenitor cell

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7
Q

What are Sharpey’s fibers ?

A

the part of any fiber that penetrated the bone and binds to periosteum

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8
Q

describe the structure of the endosteum ,

A

it is the lining of internal surface of the bone .similar in function to periosteum but only 1 layer thick (one cell thick ) and it contains immature cells .

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9
Q

what type of collagen is present in bone fibers ?

A

collagen type 1

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10
Q

extra cellular matrix of bones is not fluid it is calcified and mineralized

70% crystalline complex of calcium and phosphorus and 30% collagen

A

,,

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11
Q

what are osteoblasts ?

A

immature cells responsible for formation of bone

they are always resting on un-minaralized tissue (bone)

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12
Q

what is the matrix of oseoblasts made of?

A

glycoprotein and collagen

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13
Q

what are osteocytes ?

A

mature bone cell responsible for maintaining matrix and health of bone.

they rest on and are surrounded by lacuna ( cytoplasmic extension to communicate with other type of cell)

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14
Q

what is the lacunae?

A

cytoplasmic extension to communicate with other type of cell

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15
Q

what are ossteoclasts ?

A

the cell responsible for resorbing of bone

it is large

has multiple nucli

contains acids

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16
Q

where does the embryonic connective tissue originate from ?

A

mesoderm / mesenchyme

17
Q

what is ossification and what are the 2 types?

A

it is the formation of bone . the two types are intramembranous ossification and endochondral ossification

18
Q

what is the difference between intramembranous and endochondral ossification ?>

A

in intramembranous ossification the body draws a membrane in the shape of the desired bone ( by the mesoderm’s ) and then osteoblasts start to differentiates and form the bone inside the membrane . ( no cartilage needed)( flat bones of skull , maxilla)

in endochondral ossification a cartilage grows and the deep layer converts into bone . classification of the bone happens inside cartilage . ( vertebral column , long bones in limbs )

19
Q

what types of ossification does the mandible have ?

A

both intra membranous(body of mandible) and endochondral ossification (coronoid process and condylar process)

20
Q

which part of the mandible has intramembranous ossification ?

A

the body of the mandible .

21
Q

what part of the mandible has endochondral ossification ?

A

the coronoid and the condylar process

22
Q

what is the cartilage in endochondral ossification made of ?

A

chondroblast

23
Q

what is a lamelar bone

A

bone arranged in layer

24
Q

what are the 2 types of lamelar bone ?

A

compact bone and spongy bone

25
Q

describe the structure of compact bone.

A

has definite structure and is composed of Haversian system

26
Q

describe the structure of Haversian system

A

lamellae layers, surrounding Haversian canal . osteocytes arranged surrounding the layers of lamellae

27
Q

why and how is the bone vascularized?

A

inside the Haversian canal there are vessels

28
Q

what are canaliculi ?

A

branches coming off of the osteocytes

29
Q

what is Volkmann’s canals?

A

horizontal canal in between Haversian canal , connecting them . this is how the bone cells and blood vessels can be present inside the bone and reach into osteocytes

30
Q

complete drawing of bone under microscope on webinar 2 specialized connective tissue minute 12

A

lol

31
Q

inter statial laouter circumferential layer and inner circumferential layer . mellae

A

.

32
Q

outer circumferential layer (up next to the fibers penetrating the bone )

A

.

33
Q

inner circumferential layer( down)

A

.

34
Q

inerstacial lamella ( scattered osteocytes and lamella between Haversion system )

A

.

35
Q

how are compact and spongy bones different ?

A

lamelea are arranged keeping wide space (unlike compact bone which is compact )that contains bone marrow and is responsible for formation of hemopoietic tissue . i