Bone Healing and Fracture Nonunion Flashcards
Akagi, VCOT, 2013:
Autogenous cancellous bone and FGF-2 combined with frozen allografts in femoral nonunions
Callus formation?
Akagi, VCOT, 2013:
Callus formation was not remarkable
Minier, VCOT, 2014:
Bone regeneration in rhBMP-2 constructs vs cancellous bone autograft constructs?
Minier, VCOT, 2014:
Bone regeneration appeared to develop earlier in the rhBMP-2 constructs than the cancellous bone autograft constructs but similar results were obtained at 20 weeks post-op
Might, VCOT, 2016:
Hydrogels appeared to prevent bone growth and even caused bone lysis - true or false?
Might, VCOT, 2016:
True
Massie, VCOT, 2017:
Nonunions treated with fixation, compression resistant matrix and rhBMP-2
- Minor complication rate?
- Major complication rate?
- Functional outcomes?
- There was a delay in healing in what types of fractures?
- What was most apparent at 3-5 days post-op?
Massie, VCOT, 2017:
- 73% minor complication rate
- 18% major complication rate
- 82% returned to full function, 18% had acceptable function
- Delay in healing in humeral condylar fractures compared to diaphyseal fractures
- Significant inflammation and swelling were most apparent at 3-5 days post-op
Field and Ruthenbeck, VCOT, 2018:
- Pattern of optical density measures during fracture healing?
- Correlation between optical density measures and the qualitative measure of bridging callus and the radiographic union score for tibial fractures (RUST)?
Field and Ruthenbeck, VCOT, 2018:
- Optical density measures decreased through 4 weeks post-op (resorptive phase) and then gradually and consistently increased at 8-16 weeks post-op
- Optical density measures showed strong correlation with measures of bridging callus and RUST