Blood Pressure Regulation, Autoregulation Flashcards
Type of regulation
Accomplished by altering blood volume
Loss of blood through hemorrhage
Conservation of fluid via renal mechanism (vasoconstrictors released)
E.g. Angiotensin I converted to Angiotensin II (potent vasoconstrictor)
Aldosterone: Promotes increased reabsorption of sodium, drawing water, refilling intravascular space, conserving volume, increasing pressure
Long-term regulation
Type of regulation
Happens in the minute-minute regulation
Sympathetic and parasympathetic stimulation
Short-term regulation
Which bodily changes would increase perfusion in the capillary bed?
Low oxygen High CO2 Low pH Low nutrients Fever Decrease blood pressure (precapillary sphincter will not shunt, increasing perfusion to the bed)
Lactic acid signals
—–> PAIN
Bradykinins
Structures which collect fluid in the extravascular space and brings the fluid back in the intravascular space
Lymphatics
What is the hydrostatic pressure (push pressure) in the interstitial space?
Unit is mm Hg
1 mm Hg because of lymphatics
Pull pressure is also known as
Osmotic pressure
What happens if the fluid does not get reabsorbed?
There will be edema
Decreased perfusion in capillary bed -> Increased fluid pressure
Microcirculatory bed dysfunction