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Anatomy and Physiology - 300 > Blood Lecture 3 > Flashcards

Blood Lecture 3 Flashcards

1
Q

Blood type determined by

A

Presence/absence of specific antigens

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2
Q

Antigens

A

substances elicit immune response

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3
Q

Agglutinogen

A

Antigen that makes prod. of agglutinin

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4
Q

Agglutinins react with?

A

React with antigens if mixed incorrectly

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5
Q

Blood type determined how?

A

Which surface antigens present in RBC membranes

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6
Q

Type A blood will have which antibodies?

A

B

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7
Q

Rh+ RBC’s have?

A

Rh antigen

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8
Q

Rh- RBC’s lack?

A

Rh antigen

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9
Q

If Rh- receive Rh+ blood what happen

A

System makes anti Rh antibodies

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10
Q

If Rh- receive Rh+ second exposure what happens?

A

Agglutination and hemolysis

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11
Q

How anti-a or anti -b antibodies determined

A

Genetically

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12
Q

Transfusion is

A

transfer of whole blood or blood components

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13
Q

Where transfusion occurs

A

Into bloodstream or Red Bone Marrow

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14
Q

Transfusion used for

A

Anemia, blood volume, immunity

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15
Q

Incompatible blood transfusion causes

A

Agglutination

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16
Q

Universal recipient?

A

AB cause no antibodies

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17
Q

Universal donor?

A

Type O cause no antigens

18
Q

Hemolytic newborn disease

A

If Rh- mother has Rh+ baby, mother might create anti Rh antibodies

19
Q

What happens if mother creates anti-Rh antibodies

A

second pregnancy, antibodies cross placenta and cause agglutination

20
Q

How blood typing determined

A

Drops of blood mixed in solution with antibodies, clumping occurs

21
Q

Blood typing necessary for?

A

Avoid transfusion reactions

22
Q

Anemia

A

Oxygen carrying capacity of blood reduced

23
Q

Iron deficiency anemia

A

Inadequate absorption, or intake

24
Q

Iron deficiency anemia who’s greatest risk

A

Women

25
Q

Megaloblastic anemia due to

A

Inadequate b12 or folic acid

26
Q

Megaloblastic anemia results in

A

abnormal RBC’s, ineffective oxygen transport

27
Q

Pernicious anemia

A

Type of megaloblastic/unable to absorb b12

28
Q

Hemorrhagic anemia

A

Excessive RBC loss

29
Q

Acute blood loss

A

Increase in EPO levels

30
Q

Chronic blood loss

A

Iron stores deplete, low hemoglobin

31
Q

Hemolytic anemia

A

premature RBC plasma membrane rupture

32
Q

Thalassemia

A

Deficient hemoglobin synthesis, RBC’s small/short lived

33
Q

Thalassemia most common where

A

Mediterranean

34
Q

Sickle cell disease

A

RBC changes shape and ruptures easily

35
Q

Sickle cell disease general facts

A

Inherited, malaria belt

36
Q

Aplastic Anemia

A

Destruction of Red bone marrow

37
Q

Leukemia

A

Bone marrow cancer/ rapid WBC multiplication

38
Q

Hemophilia

A

easily Bleed with minor traumas, clotting deficiency

39
Q

Hemochromatosis

A

Body store and absorb too much iron

40
Q

Jaundice

A

Excessive biliruben in blood, yellow discoloration

Anatomy and Physiology - 300 (14 decks)

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