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Anatomy and Physiology - 300 > Blood lecture 1 > Flashcards

Blood lecture 1 Flashcards

1
Q

Cardiovascular system consists of

A

Heart, blood vessels, blood

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2
Q

Major function cardiovascular system

A

Deliver oxygen + nutrients

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3
Q

Hematology

A

study of blood,

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4
Q

Two fluids for transportation

A

Blood, interstitial fluid

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5
Q

Blood plasma

A

liquid connective tissue

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6
Q

Blood plasma composition

A

Water, plasma proteins, dissolved solutes

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7
Q

Blood transports what?

A

gases, nutrients, hormones, metabolic wastes

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8
Q

Blood regulates what?

A

pH, temperature, ion composition of IF

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9
Q

Functions of blood: protection

A

Restrict fluid loss
Defend toxins/pathogens

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10
Q

Avg. blood in adult

A

~5L

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11
Q

Whole blood =

A

blood w all components

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12
Q

2 major blood components

A

Plasma, formed elements

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13
Q

Plasma how much % of whole blood?

A

55%

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14
Q

Albumins % of plasma proteins

A

60%

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15
Q

Albumins function

A

Osmotic pressure

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16
Q

Globulins % of plasma proteins

A

35%

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17
Q

Antibodies (immunoglobins) function

A

attack foreign particles

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18
Q

Transport globulins functions

A

Bind ions, hormones, lipids

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19
Q

Fibrinogen % plasma proteins

A

~4%

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20
Q

Fibrinogen functions

A

blood clotting

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21
Q

Plasma solutes: Electrolytes

A

Essential for cellular activities

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22
Q

Plasma solutes: Organic nutrients

A

Cell ATP prod.

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23
Q

Plasma Solutes: Organic wastes

A

carried to breakdown or excretion sites

24
Q

Formed elements % of blood

A

45%

25
Q

% of formed elements RBC’s make up

A

99%

26
Q

Formed elements: Platelets %

A

<0.1%

27
Q

Formed elements: WBC’s %

A

<0.1%

28
Q

Hematocrit

A

% of whole blood from formed elements

29
Q

Lower hematocrit means

A

Anemia

30
Q

Higher hematocrit means

A

Polycythemia

31
Q

Hematopoiesis

A

How formed elements develop

32
Q

RBC’s lifespan

A

~120 days

33
Q

Hematopoiesis begins where?

A

Yolk sac - embryonic development

34
Q

Hematopoiesis switches where after yolk sac?

A

Liver, spleen, thymus

35
Q

Last 3 months pregnancy hematopoiesis happens where?

A

red bone marrow

36
Q

Red bone marrow produces?

A

RBC, WBC, platelets

37
Q

Pluripotent stem cell derived from

A

mesenchyme

38
Q

Pluripotent stem cells give rise to?

A

Lymphoid, myeloid

39
Q

Lymphoid give rise to

A

lymphocytes, natural killer cells

40
Q

Myeloid give rise to

A

neutrophils, monocytes, eosinophils, basophils, RBC, platelets

41
Q

Progenitor cells known as

A

CFU - colony forming unit

42
Q

Progenitor cells committed to give rise to

A

Specific elements of blood

43
Q

CFU-E becomes

A

Erythrocytes

44
Q

CFU-Meg becomes

A

Megakaryocytes -> platelets

45
Q

CFU-GM becomes

A

Granulocytes

46
Q

Precursor cells become

A

Actual blood cells

47
Q

Optional step: RBC (slightly immature RBC name)

A

Reticulocyte (slightly immature RBC)

48
Q

Optional step: Platelet precursor name

A

Megakaryocyte (platelet precursor)

49
Q

Hemopoietic Growth Factors are what?

A

Hormones that regulate differentiation/proliferation of CFU’s

50
Q

EPO - Erythropoetin stimulates what? and released where?

A

RBC prod. // released kidneys

51
Q

TPO - Thrombopoetin stimulates what? released where?

A

Prod. of thrombocytes // released liver

52
Q

Cytokines stimulate what?

A

WBC prod.

53
Q

Blood samples obtained via

A

venipuncture

54
Q

m/c site for venipuncture

A

median cubital vein

55
Q

Complete blood count determines

A

1 cubic ml of blood components

56
Q

WBC differential count

A

Identify # of each WBC type

57
Q

RBC tests can detect what?

A

Can detect internal bleeding

Anatomy and Physiology - 300 (14 decks)

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