Blood Borne Pathogens and PEP/PREP Lecture Powerpoint

Question 1

Which hepatitis is there a vaccine for?

Answer 1

Hep B

Question 2

Infectious body fluids that can spread HIV, HBV, or HCV (10)

Answer 2

• blood
• semen
• vaginal fluids
• amniotic fluids
• breast milk
• CSF
• pericardial fluid
• peritoneal fluid
• plural fluid
• synovial fluid

Question 3

What type of hepatitis is transmitted fecal oral route?

Answer 3

Hep A

Question 4

Mechanisms of exposure to blood borne pathogens from most common to least common in healthcare workers (4)

Answer 4

• percutaneous injury (needle sticks or sutures)
• mucus membrane exposure
• non-intact skin exposure
• bite

Question 5

Pathogen transmission of HBV vs HCV vs HIV via needle stick injury

Answer 5

up to 30%, up to 2%, up to .3%

Question 6

Hep B Ig Labs

Answer 6

• core IgM indicates acute infection
• core IgG indicates past infection (not from vaccination)
• surface antigen indicates acute or chronic infection
• surface antibody indicates had virus (if core antibody positive) or vaccine (if only positive value then vaccinated)
• E antigen indicates active viral replication and highly contagious
• E antibody indicates a carrier

Question 7

PEP Regimen for HIV (2)

Answer 7

• Raltegravir

- truvada

Question 8

PEP testing for seroconversion (6)

Answer 8

• day 0
• 6 weeks
• 3 months
• 6 months
• 1 year
• with any febrile illness

Question 9

Hep C is often transmitted with…

Answer 9

….HIV

Question 10

PREP is ___, PEP is ____

Answer 10

Truvada, truvada + raltegravir