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Mammalian Physiology > Blood > Flashcards

Blood Flashcards

1
Q

blood consists of

A

formed elements and plasma

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2
Q

plasma is

A

55%

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3
Q

formed elements

A

45%

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4
Q

plasma composed of

A

92% water, 6% proteins ( albumin, globulins, transferrin and fibrinogen) and ions, nutrients, gases, waste

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5
Q

formed elements

A

majority RBC, then WBC, and platlets

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6
Q

major contributor to colloid pressure of plasma

A

albumin

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7
Q

fibrinogen function

A

form fibre threads to blood clot

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8
Q

where are plasma proteins produced

A

liver

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9
Q

what is spectrin

A

cytoskeleton protein that binds to cytosolic side of membrane protein t, responsible for elastic strength in RBC

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10
Q

maturation of RBC takes

A

4 days

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11
Q

all blood cells are derived from

A

hematopoietic stem cells (hemocytoblasts)

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12
Q

stages of RBC

A

hemocytoblast –> basophilic erythroblasts, polychromatic erythroblasts, then lose nun to become reticulocytes

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13
Q

what creates platlets

A

fragments of egakaryocytes

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14
Q

leukopenia

A

reduction of WBC

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15
Q

reduction of RBC

A

aplastic anemia

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16
Q

destruction of RBC

A

in spleen and liver –> phagocytosis

17
Q

PCV

A

% of RBC

18
Q

normal democrat

A

45% men, 42% women

19
Q

polycythemia

A

high PCV

20
Q

neutrophils

A

phagocytic cells

migrate out of BV and enter tissue

21
Q

eosinophils

A

protect against parasites, and allergies, release anti-inflammatory substances

22
Q

basophils

A

histamine and heparin release

23
Q

hemostasis

A

stoppage of blood flow

- platelets release platelet factors, attract more and clog wound

24
Q

blood clotting mechanism

A
  1. release clotting factors
  2. formation of thrombin by prothrombin factor and calcium acting on prothrombin
  3. thrombin forming fibrin from fibrinogen
25
Q

how is blood type named

A

according to the type of antigen on the RBC

26
Q

anti- RH antibodies can appear when?

A

if mother is Rh negative, comes in contact with RH positive RBC, mother will produce anti RH antibosies, can be fatal if she has another RH positive baby

Mammalian Physiology (17 decks)

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