blood 4 Flashcards
what is anemia?
-blood has abnormally low oxygen carrying capacity
-symptom rather than disease
-blood-oxygen level cannot support normal metabolism
what are the signs/symptoms of anemia
fatigue, paleness, shortness of breath, and chills
what is hemorrhagic anemia
result of acute or chronic blood loss
what is hemolytic anemia
result of acute or chronic loss of blood
e.coli causing blood rupture (hamburger syndrome)
what is aplastic anemia
destruction of inhibiton of red bone marrow
what does iron deficiency anemia result from
- secondary result of hemorrhagic anemia
- inadequate intake of iron-containing foods
3.impaired iron absorption
how does a person get pernicious anemia? who does it affect? what is the treatment?
-Vitamin b-12 deficiency
-lack of intrinsic factor needed for absorption of b12
-stomach mucosa cells being destroyed that produce b12
-elderly and vegetarians mostly
-intramuscular injection of b12 application of nascobal (nasal spray)
what is thalassemia? how do RBCs look?
absent or faulty globin chains in Hb
RBCs are thin, delicate, deficient in Hb
What is sickle cell anemia? How do the RBCs look?
defective gene coding for an abnormal Hb called HbS.
HbS has a single amino acid substitution in the beta chain
RBCs are sickle- shaped in low oxygen situations
what is Polycythemia
excess of RBCs in blood stream increasing blood viscosity
What are the types of polycythemias
▪Polycythemia vera
▪ Secondary polycythemia (smokers, burn victims)
▪ Blood doping
▪ EPO abuse
Facts about leukocytes
-only blood component that are complete cells
- make up less than 1% of total blood volume
-leaves capillary via diapedesis
-moves through tissue space
what is leukocytosis? when would the body have that response?
when the WBC count goes over 11,000/mm. normal response to bacterial or viral invasion
how many erythrocytes are available per microliter of blood
4-6 million cells/ nano litre
how many leukocytes are available per microliter of blood
4800-10,800 cells/ nano litre