Blood 2 Flashcards

1
Q

what are the 3 formed elements

A

erthrocytes, luekocytes, and platelets

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2
Q

what are the only true cells

A

WBC’s

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3
Q

where are RBC’s made

A

red bone marrow

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4
Q

how long do blood cells last? do they divide?

A

a few day. no they are renewed in bone marrow

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5
Q

describe RBC’S characteristics

A

biconcave discs, anucleate, no organelles

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6
Q

what is the major factor erythrocytes contribute to?

A

blood viscosity

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7
Q

why are erythrocyets sometimes called a bag

A

they just hold hemoglobin which helps with gas transport

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8
Q

what does spectrin help RBC’s do

A

flex and bend, and change shape if necessary

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9
Q

how does the structural characteristic of erythrocytes help with gas transport

A

Large surface area relative to volume
97% of hemoglobin
generate ATP anaerobically and does not consume oxygen that is transported

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10
Q

Why isn’t Hb free in circulation

A
  1. increases osmotic pressure and pull water from the tissues and into the blood
  2. Kidneys are very sensitive and would damage it
  3. would lose hemoglobin to tissues where it would not longer do its job
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11
Q

RBC’s are desciated to
fighting infection
clotting blood
gas transport
trapping leukocytes

A

gas transport

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12
Q

can Hb be reversibly bound to oxygen

A

yes

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13
Q

what is the composition of Hb

A

two alpha chains, to beta chains, 4 heme groups with an iron for oxygen binding

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14
Q

What happens if one oxygen is bound

A

it encourages rapid uptake

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15
Q

what is oxyhemglobin? where does it take place?

A

Hb bound to oxygen, the lungs

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16
Q

what is deoxyhemglobun

A

hb after oxygen diffuses into tissues

17
Q

what is carbaminohemoglobin

A

hb bound to CO2

18
Q

where does Hb bind CO2

A

peptide back bone not heme

19
Q

where does CO2 loading take place

A

the tissues

20
Q

what happens to a majority of CO2

A

it is converted to bicarbonate in RBC’s by carbonic hydrnase

21
Q

what does Hematopoiesis mean?

A

blood cell formation

22
Q

where does hematopoiesis occur

A

in the red bone marrow of the axial skeleton and girdles, the epiphyses and humerus and femur

23
Q

what is the stem cell of all formed elements?

A

hemocytoblasts

24
Q

what is the order of erythropoiesis

A

hemocytoblast
proerythroblast
early erythroblast
late erythroblast
normoblast
reticulocytes
erythrocytes

25
Q

in what stage of erythropoiesis is ribosome synthesis

A

early erythroblasts phase

26
Q

in what phase is HB accumulate

A

late erythroblasts and normoblast

27
Q

when is the ejection of the nucleus?

A

normoblast and reticulocyte phase