Active transport Flashcards

1
Q

what is active transport?

A

when a cell uses energy to cross a a membrane; moving cell against concentration gradient

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2
Q

what are the two major means of active membrane transport?

A

active and vesicular

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3
Q

what is primary active transport?

A

Active transport in which ATP is hydrolyzed, yielding the energy required to transport an ion or molecule against its concentration gradient.

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4
Q

what causes an electrochemical gradient?

A

what causes an electrochemical gradient?

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5
Q

why is it important for there to be an ionic concentration difference?

A

for muscles and nerve cells to function normally and for all body cells to maintain normal fluid volume

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6
Q

How does secondary transport work?

A

by moving sodium ion across plasma membrane against its concentration gradient the pumps store energy and other substances can be dragged along the membrane like sugars or amino acids

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7
Q

What is a symport system?

A

two substances are moved across a membrane in the same direction

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8
Q

what is an antiport system?

A

two substances are moved across a membrane in opposite directions

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9
Q

what is vesicular transport?

A

flu ds containing large particles and macromolecules are transported across cellular membranes inside bubble-like, membranous sacs called vesicles

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10
Q

what is transcytosis?

A

moves substances into, across, and then
out of the cell.

  • common in blood vessels to interstitial fluid
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11
Q

what can vesicular traffickijng be compared to?

A

FedEx b/c its moves substances from one organelle in the cell to another. They need energy like vans from ATP or GTP

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12
Q

what is phagocytosis

A

cell engulf large solid material and forms a phagosome which will fuse with lysosome for digestion

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13
Q

what is pinocytosis

A

The cell gulps a drop of
extracellular fluid containing
solutes into tiny vesicles. No
receptors are used, so the
process is nonspecific

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14
Q

what is receptor mediated endocytosis?

A

-selective mechanism allowing for it to concentrate materials
- only takes small amounts
- hormones, enzyme, insulin etc.. use this route
-flu, viruses

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15
Q

what is exocytosis?

A
  • Secretion or ejection of substances from a cell.
  • The substance is enclosed in a membranous
    vesicle, which fuses with the plasma membrane (t- snares and its V snares)
    and ruptures, releasing the substance to the
    exterior.

-secretion of mucus, neurotransmitter, hormones

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16
Q

what is the concentration of potassium inside and outside of the cell?

A

5 millimolar pushing it in 150 millimolar

17
Q

what is the counter ion? why?

A

chloride to balance the outside of the cell because of the positive potassium ions acting as a buffer

18
Q

what happens as na diffuse back across the membrane

A

it uses energy left over to push other nutrient against it own gradient glucose back into the cell

19
Q

potassium has a larger leakage current leaving the cell then Sodium. T or F

A

True

20
Q

what is the membrane voltage after the ion have returned to it starting position

A

-70mV inside is negative relative to outside of cell

21
Q

what is the limitation of facilitated diffusion

A

carrier saturation

22
Q

what is the most well known substance that is transported by carrier mediated facilitated diffusion

A

glucose

23
Q

what is it called when the protein changes it shape or opening

A

confirmational change

24
Q

what takes up most of ATP consumption in neurons

A

Active transport

25
Q

why does potassium come into the cell in the first place?

A

negative charge established in the inner membrane face in it’s lasts step

26
Q

what is the membrane potential perfectly balanced for k+ when does it go back to its resting potential?

A

-90mV and returns back when sodium enters the membrane again brining it back to -70mV