Blood Flashcards

1
Q

what is blood stained with

A

romanovsky or wright wtain

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2
Q

plasma components

A

proteins- albumen, immunoglobulins, coagulation oproteins, lipoproteins, carrier proteins
mineral salts
water

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3
Q

what is serum

A

plasma without the coagulation factors

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4
Q

spectrin defects lead to ___ in RBC

A

eliliptocytosis

spherocytosis

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5
Q

rh factor

A

expression of cell surface proteins that are not A or B (C, D, E most common)

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6
Q

hemolytic disease of newborn

A

rh negative mother is sensitized from previous rh positive birth and antibodies attack RBC of second rh positive fetus

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7
Q

things affecting RBC count

A

hypoxia
hemorrhage
hormones

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8
Q

hemolytic anemia

A

early RBC destruction

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9
Q

sickle cell anemia

A

genetic mutation in hemoglobin

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10
Q

polycythemia

A

increased RBC

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11
Q

azurophilic granules

A

primary lysosomes present in all leukocytes

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12
Q

agranular leukocytes

A

lymphocytes

monocytes

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13
Q

granular leukocytes

A

basophils
neutrophils
eosinophils

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14
Q

neutrophils

A

3+ segments to nucleus

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15
Q

eosinophils

A

bilobed nucleus with coarse granules

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16
Q

specific granules in a neutrophil

A

collagenase
elastase
alkaline phosphatase
bacteriocidal enzymes

17
Q

specific granules in an eosinophil

A

acidophilic–
bacteriocidal
acid phosphatase
major basic protein

18
Q

eosinophils are most active in

A

allergic reactions and parasitic infections

19
Q

role of neutrophils

A

first line of innate defense

20
Q

basophils

A

bilobed nucleus hidden by granules

21
Q

specific granules of basophil

A

basophilic–
heparin
histamine
eosinophilic chemotactic factor

22
Q

basophil function

A

similar to mast cell– hypersensitivity reaction (bronchiole constriction and anaphylaxis)

23
Q

monoocytes

A

ruffled boarder
indented nucleus
thin rim of cytoplasm

24
Q

monocytes differentitate into

A

macorphages
microglia
osteoclasts
kupffer cells

25
Q

lymphocytes

A

round or kidney shaped nucleus with a thin rim of cytoplasm

larger than RBC

26
Q

types of lymphocytes

A

B cells
T cells
natural killer cells

27
Q

b cells mature in ____ to become ____

A

connective tissue/lymphoid tissue

plasma cells

28
Q

t cells mature in the

A

thymus

29
Q

cell platelets come from

A

megakaryocytes

30
Q

controller of platelet formation

A

thrombopoeitin

31
Q

structure of platelet

A

outer coat of glycoproteins
marginal zone of microtubules
peripheral zone (hyalomere) of actin and myosin
inner zone (granulomere) of granules

32
Q

platelet specific granules

A

lysozomal enzymes

stored serotonin taken from plasma

33
Q

coagulation proteins of platelets

A

von Hillebrand factor- factor VIII

glycoprotein 1b- factor IX

34
Q

hemophilia type A

A

defective or deficient factor VIII

35
Q

hemophila type b

A

defective or deficient factor IX

36
Q

thrombocytopenia

A

decreased platelets

37
Q

thrombocytosis

A

increased platelets

38
Q

main steps in clot formation

A
platelet plug
secondar aggregation
coagulation cascade
clot retraction
clot removal