Blood Flashcards

1
Q

what is blood stained with

A

romanovsky or wright wtain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

plasma components

A

proteins- albumen, immunoglobulins, coagulation oproteins, lipoproteins, carrier proteins
mineral salts
water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is serum

A

plasma without the coagulation factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

spectrin defects lead to ___ in RBC

A

eliliptocytosis

spherocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

rh factor

A

expression of cell surface proteins that are not A or B (C, D, E most common)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hemolytic disease of newborn

A

rh negative mother is sensitized from previous rh positive birth and antibodies attack RBC of second rh positive fetus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

things affecting RBC count

A

hypoxia
hemorrhage
hormones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

hemolytic anemia

A

early RBC destruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

sickle cell anemia

A

genetic mutation in hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

polycythemia

A

increased RBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

azurophilic granules

A

primary lysosomes present in all leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

agranular leukocytes

A

lymphocytes

monocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

granular leukocytes

A

basophils
neutrophils
eosinophils

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

neutrophils

A

3+ segments to nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

eosinophils

A

bilobed nucleus with coarse granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

specific granules in a neutrophil

A

collagenase
elastase
alkaline phosphatase
bacteriocidal enzymes

17
Q

specific granules in an eosinophil

A

acidophilic–
bacteriocidal
acid phosphatase
major basic protein

18
Q

eosinophils are most active in

A

allergic reactions and parasitic infections

19
Q

role of neutrophils

A

first line of innate defense

20
Q

basophils

A

bilobed nucleus hidden by granules

21
Q

specific granules of basophil

A

basophilic–
heparin
histamine
eosinophilic chemotactic factor

22
Q

basophil function

A

similar to mast cell– hypersensitivity reaction (bronchiole constriction and anaphylaxis)

23
Q

monoocytes

A

ruffled boarder
indented nucleus
thin rim of cytoplasm

24
Q

monocytes differentitate into

A

macorphages
microglia
osteoclasts
kupffer cells

25
lymphocytes
round or kidney shaped nucleus with a thin rim of cytoplasm | larger than RBC
26
types of lymphocytes
B cells T cells natural killer cells
27
b cells mature in ____ to become ____
connective tissue/lymphoid tissue | plasma cells
28
t cells mature in the
thymus
29
cell platelets come from
megakaryocytes
30
controller of platelet formation
thrombopoeitin
31
structure of platelet
outer coat of glycoproteins marginal zone of microtubules peripheral zone (hyalomere) of actin and myosin inner zone (granulomere) of granules
32
platelet specific granules
lysozomal enzymes | stored serotonin taken from plasma
33
coagulation proteins of platelets
von Hillebrand factor- factor VIII | glycoprotein 1b- factor IX
34
hemophilia type A
defective or deficient factor VIII
35
hemophila type b
defective or deficient factor IX
36
thrombocytopenia
decreased platelets
37
thrombocytosis
increased platelets
38
main steps in clot formation
``` platelet plug secondar aggregation coagulation cascade clot retraction clot removal ```