Block E Part 3: Hormonal Control Flashcards
What are the 4 roles of hormones?
Maintenance of the internal environment (homeostasis)
Regulation of energy metabolism
Growth and development
Reproduction
(Lecture 3, Slide 5)
What secretes the endocrine hormone into the blood?
The endocrine gland
(Lecture 3, Slide 6)
Where is the endocrine hormone carried to in the blood?
Specific target tissues or organs
(Lecture 3, Slide 6)
What are hormones in the peptide hormones family comprised of?
Chains of amino acids
(Lecture 3, Slide 7)
What are amine hormones synthesized from?
Amino acids
(Lecture 3, Slide 7)
What are steroid hormones derived from?
Cholesterol
(Lecture 3, Slide 7)
Are peptide hormones hydrophilic or hydrophobic messangers?
Hydrophilic
(Lecture 3, Slide 8)
Are steroid hormones hydrophilic or hydrophobic messangers?
Hydrophobic
(Lecture 3, Slide 8)
Where are peptide hormone receptors generally located?
On the plasma membrane of the target cell
(Lecture 3, Slide 9)
Where are steroid hormone receptors located?
In the cytosol (inside the cell)
(Lecture 3, Slide 9)
Are receptors specific to one hormone?
Yes
(Lecture 3, Slide 10)
Name 3 examples of primary endocrine organs
Pineal gland
Hypothalamus
Pituitary gland
Thyroid gland
Parathyroid gland
Thymus
Adrenal gland
Pancreas
Ovaries
Testes
Placenta (in pregnant females)
(Lecture 3, Slide 11)
Name 3 examples of secondary endocrine organs.
Heart
Stomach
Liver
Kidneys
Small intestine
Skin
(Lecture 3, Slide 11)
Why is it essential that endocrine hormones have mechanisms to switch on and off hormone secretion?
As they control various body functions
(Lecture 3, Slide 14)
What is hormonal stimulation?
Hormones released by one gland influence the secretion of other hormones
(Lecture 3, Slide 15)
What is humoral stimulation?
Blood level of ions, nutrients, bile and other compounds stimulate hormone release
(Lecture 3, Slide 15)
What is neural stimuation?
Nerve fibres activate hormone release
(Lecture 3, Slide 15)
What does the posterior pituitary contain?
Nerve endings of neurones originating in the hypothalamus
(Lecture 3, Slide 16)
What is the role of the anterior pituitary?
Synthesises and secretes trophic hormones
(Lecture 3, Slides 16 and 18)
What are trophic hormones?
Hormones that control the secretion of other hormones
(Lecture 3, Slides 15 and 18)
What are the common names of the two primary hormones secreted by the thyroid gland?
T3 and T4
(Lecture 3, Slide 20)
What are the 3 purposes of thyroid hormones?
Increase metabolic rate (by regulating heat production and oxygen consumption)
Increase activity of the cardiovascular system
Stimulate growth and development
(Lecture 3, Slide 22)
What is hypothyroidism?
Low levels of thyroid hormones
(Lecture 3, Slide 23)
What 3 things does hypothyroidism lead to?
Weight gain
Lethargy (lack of energy and enthusiasm)
Oedema (swelling due to fluid accumulation)
(Lecture 3, Slide 23)
What is hyperthyroidism?
High levels of thyroid hormones
(Lecture 3, Slide 23)
What 3 things does hyperthyroidism lead to?
Weight loss
Sweating
Eye abnormality
(Lecture 3, Slide 23)
What are normal blood glucose levels before meals?
4-5.9 mmol/l
(Lecture 3, Slide 29)
What does blood glucose rise to 2 hours after a meal?
7.8 mmol/l
(Lecture 3, Slide 29)
What is hyperglycaemia?
High blood glucose
(Lecture 3, Slide 29)
What level is blood glucose in hyperglycaemia?
Above 11mmol/l
(Lecture 3, Slide 29)
What are 2 symptoms of hyperglycaemia?
Being thirsty
Polyuria (frequent urination)
Tiredness
Diabetic coma
(Lecture 3, Slide 29)
What is hypoglycaemia?
Low blood glucose
(Lecture 3, Slide 29)
What level is blood glucose in hypoglycaemia?
below 2.5 mmol/l
(Lecture 3, Slide 29)
What are 3 symptoms of hypoglucaemia?
Dizziness
Weakness
Drowsiness
Confusion
Diabetic coma
(Lecture 3, Slide 29)
What is type I diabetes?
Loss of insulin secreting cells
(Lecture 3, Slide 30)
What do people will type I diabetes require?
Daily injections of insulin
(Lecture 3, Slide 30)
What are 2 long term complications of type I diabetes?
Cardiovascular disease
Damage to eye (retinopathy)
Damage to kidney (nephropathy)
Damage to nerves (neuropathy)
(Lecture 3, Slide 30)