Block C Part 1: Bacteria, Viruses and Parasites Flashcards
What is a pathogen?
An organism that causes disease
(Lecture 1, Slide 3)
State 3 ways in which pathogenic effects can vary
Between organisms
Severity
May be acute or chronic
Can effect different parts of the body
Can be restricted to certain populations due to their genetic material
(Lecture 1, Slide 3)
How big are virions?
Viruses are sized from 10nm up to 400nm
(Lecture 1, Slide 5)
What type of microscope do you need to see a virus?
An electron microscope
(Lecture 1, Slide 4)
What forms the core of a virus?
One or two molecules of DNA or RNA
(Lecture 1, Slide 5)
What is a capsid?
RNA/DNA enclosed in a protein coat on a virus
(Lecture 1, Slide 5)
What is the outer layer of a virus called (if it has one) and what does it contain?
The envelope and it can have lipids, proteins or carbohydrates in it
(Lecture 1, Slide 5)
What is a virus particle called?
A virion
(Lecture 1, Slide 5)
What is the 1st Stage of the life cycle of a virion?
Extracellular virion enters cell and begins it’s intracellular phase
(Lecture 1, Slide 5)
What is the 2nd stage of a life cycle of a virion?
Specific cell target “virus factory” - release virions
(Lecture 1, Slide 5)
To combat a virus, what 3 things will you have to control?
Virus particles (virions), Virus infected cells and viral toxins
(Lecture 1, Slide 6)
What is measles?
A viral infection caused by infection with the measles virus, an enveloped single-stranded RNA virus
(Lecture 1, Slide 8)
How do you become infected with measles?
By inhaling droplets with the virus inside
(Lecture 1, Slide 8)
What can measles effect and cause?
It can effect your hearing and throat, and can result in pneumonia, diarrhea, seizures and swelling of the brain
(Lecture 1, Slide 9)
What can virus-induced immunosuppression from measles lead to?
It can allow other opportunistic infections to flourish which can lead to the central nervous system being effected, comas, and death
(Lecture 1, Slide 9)
What is the primary viraemia of measles?
The virus spreads to regional lymph nodes
(Lecture 1, Slide 10)
What is the secondary viraemia of measles?
Virus disseminated to other sites in the body
(Lecture 1, Slide 10)
What 5 cells can the measles virus live in?
Dendritic cells, monocytes, lymphocytes, epithelial cells and endothelial cells
(Lecture 1, Slide 10)
What size are bacteria?
Microscopic
(Lecture 1, Slide 11)
Are bacteria intracellular, extracellular or both?
Both
(Lecture 1, Slide 10)
Are bacteria free living or parasitic or both?
Both
(Lecture 1, Slide 10)
What are the 3 main shapes of bacteria?
Rod, spherical and spiral
(Lecture 1, Slide 11)
Are Bacteria prokaryotes or eukaryotes?
Prokaryotes
(Lecture 1, Slide 11)
Where is the DNA in a bacteria located?
In the cytoplasm
(Lecture 1, Slide 11)
What size are fungi and their spores?
Fungi are visible to the human eye but their spores are microscopic
(Lecture 1, Slide 15)
What do fungi produce?
They produce fruiting bodies
(Lecture 1, Slide 15)
What do fungi spores do?
Spores germinate to produce a mycelium
(Lecture 1, Slide 15)
How are fungi spores dispersed?
They are dispersed by wind/animals
(Lecture 1, Slide 15)
What 3 things must the immune response must control to combat a fungi?
Budding yeast cells, Pseudohyphae and Hyphae
(Lecture 1, Slide 18)
What 4 ways can parasitic infections vary?
Can be multi or unicellular
Can be intra or extracellular
Can vary in size
Can live in various locations
(Lecture 1, Slide 24)
What causes a parasitic infection?
When the immune system cannot control the parasite
(Lecture 1, Slide 24)
What are the 3 different routes a parasite infect by?
They can infect by using active mechanisms, use an intermediate host, or use a vector
(Lecture 1, Slide 26)
How can intracellular parasites kill cells?
They can kill by activating or eliminating the infected cell
(Lecture 1, Slide 27)
How do you kill gut extracellular parasites?
Need to be expelled
(Lecture 1, Slide 28)
How do you kill tissue parasites?
They need to be damaged and broken down
(Lecture 1, Slide 28)
What does the killing of extracellular parasites require?
Co-operation between a range of cells and other mechanisms
(Lecture 1, Slide 28)
What are the 2 impacts of hookworms?
They impair the physical and intellectual development of children and effect economic development of communities
(Lecture 1, Slide 37)
What do fruiting bodies produce?
Spores
(Lecture 1, Slide 15)