Bitches be Crazy

Question 1

What is a parasitic infection caused by the introduction of the protozoan organisms into the blood by the bite of a female anopheles mosquito

Answer 1

Malaria

Question 2

What is plasmodium?

Answer 2

Malaria Parasite

Question 3

What mosquito causes malaria?

Answer 3

Female Anopheles

Question 4

What gets injected when bitten?

Answer 4

Sporozoites

Question 5

Where do the sporozoites go?

Answer 5

Parenchymal cells of liver to become schizonts

Question 6

What is the initial development in the liver?

Answer 6

Pre-ertyhrocytic cycle

Question 7

What is further development in the liver after RBC invasion?

Answer 7

Exoeruthrocytic cycle

Question 8

What do schizonts feed on?

Answer 8

Hgb

Question 9

What is the pigment of Hgb when fed on?

Answer 9

Malarial pigment

Question 10

What is the malarial pigment made up of?

Answer 10

Hematin and protein

Question 11

What causes elevated temperatures in the body?

Answer 11

Increased levels of schizonts

Question 12

What causes the ring forms?

Answer 12

Schizonts

Question 13

What is developed when things ruptured?

Answer 13

Merozoites

Question 14

At some point a gametocyte is produced which is then ingested by a mosquito, what happens then?

Answer 14

Beginning of sexual reproduction – production of zygote

Question 15

Where can all stages of asexual cycle be demonstrated?

Answer 15

peripheral blood except P. Falciparum

Question 16

What happens when only rings and gametocytes?

Answer 16

RBC membrane becomes sticky as parasite matures

2 Cells adhere to endothelial lining of capillaries of internal organs 3 Interferes with normal blood flow.

Question 17

What happens when ring form of P. Falciparum - light blue circular structures with red chromatin dot.?

Answer 17

• Double chromatin dots
• multiple ring froms
• marginal or applique
• RBC- usually normal

Question 18

What do ring form of P. Falciparum look like?

Answer 18

• light blue circular structures with red chromatin dot

Question 19

What do you see for gametocute of p. falciparum?

Answer 19

• curved sausage/ banana shaped with central large chromatin dot covered with centralized mass of hemazoin.
• shorter and wider than female with rounded ends, diffused chromatin seen with hemazoin granules.
• RBC may be attached to gametocyte.

Question 20

Is Gametocyte of P. falciparum considered diagnostic?

Answer 20

Yes

Question 21

It is observed that the fever cycle corresponds to the Erythrocytic Schizogony cycle for each of the malaria species

Answer 21

True

Question 22

What are the 4 types of malaria?

Answer 22

• Plasmodium Falciparum (malignant)
• Plasmodium Vivax ( Benign)
• Plasmodium Ovale (benign)
• Plasmodium Malariae (benign quartan)

Question 23

What is the most fatal type?

Answer 23

Plasmodium Falciparum, with fever every 48 hours

Question 24

What is the most common type?

Answer 24

Plasmodium Vivax

Question 25

What’s the only type that has a fever every 72 hours?

Answer 25

Plasmodium Malariae

Question 26

What does Plasmodium Falciparum do to the RBCs?

Answer 26

Intravascular hemolysis (destruction of RBCs)

Question 27

What methods are used for blood collection?

Answer 27

Capillary or Venous

Question 28

What tube is used for venous

Answer 28

EDTA (Purple)

Question 29

How long will blood sample be stored?

Answer 29

2C to 30C for 3 days