Bisphosphonate Flashcards
1
Q
Stabilizes hydroxyapatite structure
Induce osteoblast to secrete inhibitors of osteoclast
Slows progress of osteoporosis
A
Bisphosphonate Alendronate Etidronate Pamidronate Risedronate
2
Q
Peptide hormone by thyroid gland
Decreases bone resorption
Decreases serum calcium and phosphate
A
Paget’s disease
Hypercalcemia
3
Q
Osteitis deformans pathologic fracture
A
Mosaic lamellar bone pattern
4
Q
Etidronate and pamidronate SE
A
Bone mineralization defect (lose effectiveness after 12 months)
GI distress including esophageal ulcers (aledronate)
5
Q
Drug for OCP induced osteoporosis
A
Alendronate
6
Q
Osteoporosis type of fx
A
Subcapital
7
Q
Bisphosphonate indications
A
Paget disease
Postmenopausal osteoporosis
Alendronate is the DOC for steroid-induced osteoporosis
