Bipolar Disorders Flashcards
Involve extreme mood swings from episodes of mania to episodes of depression
Bipolar Disorders
severe mood elevation, expansion, or irritability that causes impairment in social or occupational function
Mania
Mania last for how long?
Must last at least one week
a milder form of mania
Hypomania
Hypomania must present for how long?
Must be present for at least 4 consecutive days
neutral mood
Euthymia
Manic Phase Symptoms
-Brightly colored clothing
-Flamboyant
-Sexually suggestive
-Attention:getting
-Pressured speech
-Difficulty sitting still
Unrelentingly rapid and often loud speech without pauses
Pressured speech
What are the types of Bipolar Disorders?
-Bipolar I Disorder
- Bipolar II Disorder
- Cyclothymia
Depression + Mania
Bipolar I Disorder
Depression + Hypomania
Bipolar II Disorder
Chronic mood disturbance for at least 2 years
Cyclothymia
Theoretical Basis (Genetics)
-First-degree relatives of people with BP-1 are approximately 7 times more likely to develop BP-1 than the general population.
- Offspring of a parent with bipolar disorder have a 50% chance of having another major psychiatric disorder.
-Twin studies demonstrate a concordance of 33-90% for BP-1 in identical twins.
Serves as defense against the feelings of depression
Mania
May impact the onset of bipolar disorder, particularly in those patients with a family history of mood disorders
Large increase in springtime solar insolation
Management for Bipolar Disorders
Mood Stabilizers
-Lifetime treatment
-Can prevent acute cycles of bipolar behavior
-Regimen involves lithium, anticonvulsants, and atypical antipsychotics
The mechanism of action of Lithium Carbonate (Eskalith)
Normalizes reuptake of serotonin, NE, and Dopamine
The Lag Period of Lithium
5 to 14 days
Must know in Lithium
-Not metabolized and is excreted via urine
-Completes for salt receptor sites
-May elevate TSH levels
Lithium therapeutic range in acute mania
0.8 to 1.5 mEq/L
Lithium therapeutic range in maintenance
0.5 to 1.0 mEq/L
On what level toxicity occurs
Toxicity occurs at 1.5 mEq/L
Causes of Lithium Toxicity
-Dose is too high
- Diarrhea, vomiting
- Diaphoresis
- Dehydration
Range of Mild Lithium Toxicity
1.5 to 2.0 mEq/L