Bipolar Disorder and Dementia Flashcards
What is the treatment of Acute Bipolar Disease
- Benzodiazepinenes
- Antipsychotics
- Lithium
- Sodium Valproate
What is the prophylaxis of Bipolar Disease
- Carbamazepine
- Lithium
- Sodium valproate
Summarised Lithium Toxicity
Sick and Tremor
Summarised Digoxin Toxicity
Sick and Slow
Summarised Theophylline Toxicity
Sick and Fast
What is the therapeutic range for Lithium
0.4 to 1 mmol/L
When should you measure Lithium serum levels
12 hours after dose
==> weekly until stable
====> 3 monthly for 1 year
======> 6 monthly after that
What are the stand out Lithium toxicity signs
- extrapyramidal side effects
- visual disturbances
- confusion and relentlessness
What are Lithium side effects
- Thyroid disorders
- Nephrotoxicity
- Rhabdomylosis
- Intercrainial Hypetension
Which trimester is Lithium teratogenic in
1st
Lithium Interactions
- hyponatraemic drugs
- drugs that cause extrapyramidal side effects
- QT prolongation drugs
- drugs that are nephrotically cleared
- drugs that reduce seizure threshold
What is the treatment for Mild to Moderate Dementia
- Donepezil
- Rivastigmine
- Galantamine
What is the treatment for severe Dementia
Memantine
Which drug class is used to treat dementia
Acetylcholinesterase inhibitors
What is the Mnemonic for side effects of Acetylcholinesterase inhibitors
DUMB BELS
