Biopsy 7 Flashcards
Are hibernation and migration a slow cirannual rhythms or fast rhythms?
Slow circannual rhythms
What result to slow circannual rhythm?
movement of the earth around the sun
Are heart rate and Temp. fast(ultradian) rhythm?
Yes
What rhythm is the sleep-wake cycle?
Daily (circadian) rhythm
What does the bunker experiment show?
Even there are no cues about light and dark, subject inside the bunker wake up about the same time as outside the bunker.
—> We have a Biological clock that governs sleep-waking cycle
In the absence of external cues, how long does the sleep-wake cycle last for?
26 hours
Sleep-wake cycle matches Day-night cycle (24hrs). What does this suggest?
Endogenous rhythmicity is not the only factor for circadian periods.
What is Zeitgebers (time-giver) ?
Environmental events/ natural cues that regulate biological circadian rhythms
e.g. light
What is jet lag & when is more pronounced?
- disruption to the biological clock
- from west to east is more pronounced
Why is jet lag less pronounced when travelled from east to west?
Because the biological clock has a natural period of longer than 24 hrs
Explanation for SAD.
Lack of light signals hibernation —> disruption to circadian rhythm
How to prevent SAD?
Sit in front of a bank of bright light for 20 mins a day
Possible location of endogenous circadian rhythm?
SCN - suprachiasmatic nucleus
of the hypothalamus
Why SCN is suggested to be the location of endogenous circadian rhythm?
When it is disconnected from the brain, its neurons continue to show fluctuations in neuronal activity
How does light direct the rhythmic activity of SCN?
SCN receives direct input of light from the retina
SCN is not the only biological clock, but a ___?___ for other rhythms.
pacemaker
Can animals get a normal circadian rhythm again if they got a transplanted SCN?
Yes
What is secreted during the dark phase of sleep-wake cycle and by which gland?
Pineal gland secretes melatonin
Is it a direct or indirect action of SCN for pineal gland to secrete melatonin?
Indirect action
Which hormone can be used to treat jet lag/ reset body clock artificially?
Melatonin
State another action of SCN on other glands.
adrenal glands —> to release ‘mood & alertness altering hormones’, e.g. cortisol
Circadian rhythm changes according to __?__ and reason why?
- age
- Adolescence causes melatonin to be delayed
How to solve the changes in circadian rhythm?
- changes the schedule
- change via light and SCN
State the primary measure of sleep stages and describe the activity patter.
- EEG
- Awake: Low amplitude, high frequency
- Deep sleep: High amplitude, low frequency
- REM: low amplitude, high frequency
Describe the body changes in Non-REM sleep.
- body Temp. declines
- heart rate decreases
- rowth hormones increase