Biomolecular interactions Flashcards

1
Q

What is surface plasmon resonance?

A

Coherent delocalised electron oscillations at interfaces

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2
Q

How does surface plasmon resonance work?

A

Interaction between the analyte with ligands causes changes to the SPR wave which alters the angle of reflection of the incident light

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3
Q

What are the changes to the SPR wave proportional to?

A

The mass of the analyte thus a smaller analyte will give lower signal levels

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4
Q

What are the sensor chips?

A

A surface for the immobilisation of ligands on the surface

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5
Q

KD calculation

A

KD=Kd/Ka

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