Biology Topic 2 Flashcards
what are lungs
an organ adapted for gas exchange
what is another word for breathing
ventilation
what are alveoli
the site of gas exchange
why do we as humans need lungs
larger and more complex organisms have a smaller surface area to volume ratio and low diffusion distance from skin to organs
how do smaller organisms perform gas exchange if not through lungs
through the skin
why can small organisms afford not to have lungs
they have a large surface area to volume ratio so they can rely on diffusion from the air to perform gas exchange through the skin
what is the movement of the ribcage during inhalation
up and out
what is the movement of the diaphragm during inhalation
contracts and moves down
what is the change in chest volume during inhalation
increase
what is the movement of the ribcage during exhalation
down and in
what is the movement of the diaphragm in exhalation
relaxes and moves up
what is the change in chest volume during exhalation
decreases
what proportion of CO2 is inhales
0.04%
what proportion nitrogen is inhaled
78%
what proportion oxygen is inhaled
21%
what proportion of O2 is exhaled
17%
what proportion Co2 is exhaled
4%
what proportion nitrogen is exhaled
78%
give 4 adaptions of the alveoli to diffusion
well ventilated
lots of them and they are folded
good blood supply
one cell thick cell wall
how does the alveoli being well ventilated help with diffusion
maintains steep concentration gradient
how does having lots of alveoli and them being folded help with diffusion
increases surface area over which diffusion can occur
what does a good blood supply do to help with diffusion in the alveoli
maintains steep concentration gradient
what does a one cell thick cell membrane in the alveoli do to help diffusion
short diffusion pathway enables more diffusion
can you label a diagram of the lungs?
well done!
what type of circulatory system do humans have
double circulatory system
what are the two circuits of the double circulatory system
systemic and pulmonary circuits
what organ does the pulmonary circuit pass through
the lungs
the systemic circuit goes through lungs/body
body
where does the pulmonary artery go
to the lungs
where does the pulmonary vein go
to the heart
where does the vena cava go
to the heart
where does the aorta go
to the body
give the stages of the circulatory system starting with the vena cava
vena cava comes from body to heart
pulmonary artery takes blood to lungs
pulmonary vein carries it back to the heart
aorta carries it to the body
which two blood vessels carry deoxygenated blood
vena cava and pulmonary artery
which two blood vessels carry oxygenated blood
aorta and pulmonary vein
blood is oxygenated where
in the lungs
what is the biggest vein in the body
vena cava
what is the largest artery in the body
aorta
the aorta runs at high or low pressure
high
which side of the heart has deoxygenated blood
the right
which side of the heart has oxygenated blood
the left
the heart is labelled from whose point of view - above or as if you are lying down
as if you are lying down
make sure to swap left and right sides
the heart is a ____
muscle
what type of muscle is the heart made of
cardiac muscle
what keeps oxygenated and deoxygenated blood separate
septum
what is the heartbeat controlled by
cells in the right atrium
where are the pacemaker cells located
right atrium
which of the two (left or right ventricle) has a thicker wall
left ventricle
why is the left ventricle thicker than the right
it needs to increase blood pressure to pump oxygenated blood around the body
can you label a heart?
well done!!
the vena cava feeds into what chamber of the heart
right atrium
the right atrium is linked to what blood vessel
the vena cava
the right ventricle links to what blood vessel
pulmonary artery
the pulmonary artery links to what chamber of the heart
right ventricle
the pulmonary vein links to what chamber of the heart
left atrium
the aorta links to what chamber of the heart
left ventricle
the left atrium links to what blood vessel
pulmonary vein
the left ventricle links to what blood vessel
aorta
how to cells in the right atrium make the heart beat
they trigger electrical impulses
the heart muscle is supplied blood by what ___
coronary arteries
what do coronary arteries supply to the heart
oxygen and glucose
what does CHD stand for
coronary heart disease
what is the issue with CHD
plaque containing cholesterol builds and narrows the lumen of arteries
what is it called when plaque builds up in coronary arteries/more general blood vessel
Atherosclerosis
what is an irregular heart rate (or too fast or too slow) condition known as
arrhythmia
what is arrhythmia treated with
a pacemaker
if heart rate is too fast what happens to blood pressure
too high
give 3 risk factors for CHD
smoking
obesity
high cholesterol
if heart rate is too slow what happens and what condition is this due to
arrhythmia
low blood pressure - insufficient flow of blood and oxygen around the body
what is the issue with a faulty heart valve
chambers don’t shut slo blood can’t be pumped effectively and efficiently
what is heart failure
when damage to the heart causes reduced rate of blood flow
give 3 possible treatments for coronary heart disease
statins
bypass
stent
what are statins
drugs that reduce cholesterol levels in the blood
what is cholesterol
level of fat
give 3 advantages of statins
doesn’t require surgery
easy to take
can be successful
give 2 disadvantage of statins
side effects
expensive for the NHS as its a long term thing
give 3 side effects of statins
headaches
sleeping issues
muscle pain
what is a bypass for treating CHD
adding extra blood vessel capacity (vein usually transplanted from another area of the body)
where do the surgeons get the vein for treating CHD with a coronary bypass
another part of the body
give an advantage of bypass surgery
high success rate
give 2 disadvantages of bypass surgery
may need to be done repeatedly
surgery can cause stroke or heart failure
what is a stent
an inserted small metal mesh tube that widens artery lumen size to restore blood flow to the heart
stents treat early stage/advanced CHD?
advanced
true or false: stents are not used to treat heart attacks
false - they are
give an advantage of a stent
immediately relieves condition
give 2 disadvantages of a stent
can trigger blood clots (and another heart attack therefore)
requires surgery
what is the treatment for arrhythmia
artificial pacemaker to regulate heart rate
give an advantage of artificial pacemaker
low risk procedure
can be successful and massively increase quality of life
give 3 disadvantages of an artificial pacemaker
requires surgery - with risk of infection
battery need replacing
you have to be careful around electromagnetic fields
give 2 possible treatments for leaky valves
mechanical valve replacement
biological valve replacement
give an advantage of mechanical valve replacement
they last a long time
give 3 disadvantages of mechanical valve replacement
can cause blood clots
can damage red blood cells
and so patient has to take blood thinners
what 3 animals can a biological valve replacement come from
pig, cow or human
give 2 disadvantages of biological valve replacement
some patients have religious objections to it
only last 12-15 years
give 2 advantages of biological valve replacement
you don’t have to take blood thinners
(it doesn’t damage red blood cells or lead to clotting)
give 2 possible treatments for heart failure
heart transplant
artificial heart
give a disadvantage of an artificial heart
only a short term fix
give 2 advantages of an artificial heart
won’t be rejected by the body
helps a person that needs a transplant very quickly
give 3 disadvantages of a biological heart transplant
you have to take immunosuppressants for the rest of your life
they are in short supply
there is a risk of rejection
give 2 advantages of a biological heart transplant
doesn’t need to be replaced
allows a person to live after heart failure
what is heart rate measured in
beats per minute
how is cardiac output calculated
stroke volume x heart rate
what is cardiac output measured in
ml/min
what is stroke volume measured in
ml/beat
is blood a cell, tissue or organ
tissue
where is blood made
in the bone marrow
how many components to blood are there
4
what % of blood are red blood cells
45%
what do red blood cells do
deliver oxygen to the body’s cells for respiration
red blood cells don’t have a what
nucleus
why don’t red blood cells have a nucleus
to have more space for oxygen absorption and storage
what shape to red blood cells have
biconcave shape
why do red blood cells have a biconcave shape
to have a large surface area for maximum oxygen absorption
what do red blood cells contain
haemoglobin
what mineral does haemoglobin contain
iron
what makes red blood cells red
haemoglobin
what substance is actually carried in the red blood cell when it picks up oxygen
oxyhemoglobin
what does haemoglobin do in the red blood cell
helps absorb oxygen
what is the function of white blood cells
defends body against infections caused by pathogens
what is the % composition of white blood cells in blood
less than 1%
what % of white blood cells are phagocytes
70%
what does phago mean
eat
what do pathogens contain
enzymes to digest and destroy pathogens
why don’t phagocytes kill pathogens?
they may not be living so they destroy them instead
what is the function of phagocytes
to engulf pathogens by engulfing and digesting them
how do phagocytes destroy pathogens
a pit is formed which the pathogen enters
it is engulfed by the phagocyte as part of phagocytosis
then digested by digestive enzymes
then the remains of the pathogen are absorbed
what is phagocytosis
when the phagocyte engulfs the pathogen
what % of white blood cells are lymphocytes
25%
what is the function of lymphocytes
to create antibodies which cause agglutination and bind to antigens to mark them out for phagocytosis
and release anti toxins to neutralise toxins
what is a third category in white blood cells that is often forgotten
memory cells - ironic
what are memory cells
differentiated white blood cells which respond quickly to pathogens by releasing antibodies
what is the process of making pathogens stick together so its easier for phagocytes to destroy them
agglutination
what are the proteins on pathogens called
antigens
which one attacks/attaches to which: antigens and antibodies
antibodies attacks to antigens - remember that as b comes before g in the alphabet
what is the function of platelets
to clot blood at a wound to prevent loss of blood and stop micro organisms entering the body via the wound
what 2 bad things to platelets prevent
loss of blood
microorganisms entering the body via the wound
what are platelets
small fragments of cells that can clump together and clot due to proteins on their surface
what enables platelets to clot
proteins on their surface
what do platelets not have
a nucleus
give 3 adaptions of the platelets to function
no nucleus
can change shape to form different clots
secrete blood clotting proteins
how does having no nucleus help a platelet to function
makes it smaller
easier to change shape
what is the function of the plasma
liquid part of the blood that suspends cells and platelets
also transports dissolved substances such as antibodies, hormones, CO2, glucose etc
give 3 things the plasma transports
hormones
antibodies
CO2
Oxygen
glucose
what is the % composition in the blood of the plasma
54%
give 2 pros of blood donation
helps those with blood loss/leukaemia
no risk of infection in the UK due to screening procedures
give 2 cons of blood donation
hepatitis C and HIV can be passed on and infect the receiver
procedure can be painful for the donor and lead to weakness or fainting
what 2 conditions can be passed on by blood donation
hepatitis C and HIV
what 2 things can the process of donating your blood lead to
weakness and fainting
what is another word for blood donation
blood transfusion
give 4 features of arteries
smaller lumen diameter
thicker wall of muscular and elastic tissue
thicker connective tissue walls
carries blood at high pressure
why do arteries have smaller lumen diameters
helps maintain high blood pressure
what does the thick wall of muscle and elastic tissue do for arteries
expands and recoils to pulse blood
arteries carry blood at high/low pressure
high
what is the function of arteries
to carry blood away from the heart
arteries carry blood to or from heart
from
give 2 things that maintain high blood pressure in the arteries
thick walls of muscle and elastic tissue and narrow lumen
give 3 features of veins
blood travels at low pressure
larger lumen with irregular shape
thin and weak wall
blood in veins travels at a high/low pressure
low
blood in veins has a smaller/larger lumen with a regular/irregular shape
larger
irregular
describe the walls of veins
thin and weak
what is a venous pump
pressure in veins is too low to flow back to the heart on its own so skeletal muscles contract to move blood by squeezing veins
what parts of the body squeeze veins to move blood around the body
skeletal muscles
veins carry blood to/from the heart
to
how do you remember that arteries carry blood from the heart
arteries = away
give 2 features of capillaries
one cell thick
narrow lumen
what does a one cell thick capillary help capillaries do
have a short diffusion pathway
name 3 things that diffuse through blood capillaries
oxygen, glucose, amino acids, hormones
what size lumen do capillaries have
narrow
a capillary ___runs through organs and muscles
bed
capillary beds have a large _____for efficient diffusion/gas exchange
surface area
what is the function of capillaries
carry blood to and from the body’s muscles and organs
what is the lumen
the tube part of the blood vessel
what do valves do
make sure blood only travels in one direction
where are valves located in blood vessels
in the lumen
give 3 points you could use in a comparative 6 marker about arteries vs veins
wall thickness
lumen size
blood pressure
in a comparative 6 marker what kind of words should you include
comparative words like whereas/however
and more/less/stronger/larger etc
name 4 reagents
Benedict’s SOLUTION
iodine SOLUTION
Biurets SOLUTION
ethanol/sudan III
what word should you include after the name of every reagent
solution
what is the starting colour of beneditcs solution
blue
what is the original colour of iodine
orange
what is the original colour of biurets solution
light blue
what is the original colour of ethanol/sudan III
colourless
what is a strong positive result for Benedict’s solution test
brick red
what is a medium positive result for Benedict’s solution
orange
what is a weak positive result for Benedict’s solution
yellow