B5-7 Spec Flashcards
what kind of cells are formed as a result of meiosis
non identical cells
what kind of cells are formed as a result of mitosis
identical cells
what is sexual reproduction in terms of cells
fusion of male and female gametes
what are the two gametes in animals
sperm and egg
what are the two gametes in plants
pollen and egg cells
how are gametes formed
meiosis
in sexual reproduction there is a ___of genetic information which leads to ____in the offspring
mixing
variety
asexual reproduction has how many parents and how much fusion of gametes and how much mixing of genetic information leading to genetically____offspring and only___is involved
1 parent
no fusion of gametes
no mixing of genetic information
identical
mitosis
describe meiosis and where does it happen and what does it produce
reproductive organs
gametes
normal cell makes copies of genetic information
cell divides twice to form 4 gametes - each with a single set of chromosomes
all gametes are genetically different from each other
when meiosis forms gametes are they the same genetically or different?
all are different
gametes join at ___to restore the __number of chromosomes
fertilisation
normal
after fertilisation cells divide by ___. as the embryo develops cells ____
mitosis - differentiate
homeostasis definition
regulations of the internal condition of a cell or organism to maintain conditions for function in response to internal and external changes
give 2 reasons homeostasis is important
to maintain optimum conditions for enzyme activity
and cell function
what does homeostasis maintain levels of
glucose
water
temperature
what things are involved in automatic control systems (two ways of responding to internal or external conditions)
nervous responses or chemical responses
what is a receptor for
to detect stimuli
what are coordination centres for
receive and process information from receptors
what are 3 coordination centres
spinal chord
brain
pancreas
what are effectors for
bring about a response to restore optimum conditions
what 2 things could effectors be
muscle or gland
what does the nervous system allow humans to do
react to surroundings and coordinate behaviours
reflex arc of touching something hot
stimulus of hot thing
receptor of skin
sensory neurone detects it
information passes along the neurones as electrical impulses
CNS (using relay neurones) coordinates the response of the effectors (spinal chord)
motor neurones causes muscles to contract and pull away
why are reflexes important
to keep us safe from harm and prevent injury
how is information transferred between neurones
it passes along neurones as electrical impulses
what are reflex actions
do not involve the conscious part of the brain
they are automatic and rapid
ruler drop experiment control variables
caffeine intake
sleep
age
eyesight/disabilities
(ensure hand at bottom of ruler)
what is a risk of the ruler drop experiment
risk of drinking too much caffeine which could cause unpleasant side effects
what is another variation of the ruler drop experiment
use computer software to find reaction time - reaction to a stimulus
why are computers more accurate
remove possibility of human error
why are computers more precise
computer can record reaction time in milliseconds - kind of interchangeable with the accuracy one
3 advantages of sexual reproduction
produces variation
variation gives a survival advantage by natural selection if the environment changes
natural selection can be sped up by humans in selective breeding to increase food production
advantages of asexual reproduction
only 1 parent needed
more time and energy efficient (as don’t need to find mate)
faster
many identical offspring can be produced - when conditions are favourable
how do malarial parasites reproduce in the human host
asexually - as can’t get any gals in the human
how do malarial parasites reproduce in the mosquito
sexually
how do fungi do asexual reproduction
by spores - but they can also reproduce sexually!!
give 3 examples of things that can reproduce both sexually and asexually
plants
fungi
malaria
how do plants reproduce sexually
using seeds
give 2 examples of plants that reproduce asexually - and the process of their asexual reproduction
bulb division such as daffodils
runners such as strawberry plants
define genome
entire genetic material of an organism
what is the structure of DNA
double helix - two strands
what type of thing is DNA
polymer
what is DNA contained in
the nucleus
chromosomes
what is a gene
small section of DNA on a chromosome
each gene codes for what
a particular sequence of amino acids to make a specific protein
the whole human genome has been what and what is this greatly important for
studied
medicine in the future
give 3 reasons it is important to understand the human genome
search for genes linked to different types of disease
understand and treat inherit disorders
trace human migration patterns from the past
why is understanding the human genome linked to tracing past migration patterns
understanding common ancestor in Africa
tracing how new populations split off leading to tiny differences in genomes
what is DNA made from
4 different nucleotides
what is a nucleotide comprised of
sugar - pentagon
phosphate group -cirlce
1 base - square
what are the 4 bases
ACTG
How many bases in one amino acid
3
how do bases control production of a protein
the order controls the order of
amino acids being assembled
DNA consists of alternating what
sugar and phosphate sections
what is C linked to and what is A
C=G
A=T
where are proteins synthesised
ribsomomes
how are proteins synthesised
carriers molecules
bring specific amino acids
in the correct order to form a
protein chain
when the protein chain is complete what happens
it folds to form a unique shape
why is it important that proteins have a unique shape
this enables the proteins to do their job (as enzymes, hormones or structure forming proteins like collagen)
give 3 examples of proteins
hormones, enzymes and collagen
how often do mutations occur
continuously
what do most mutations do
either don’t alter protein
or alter so slightly that appearance or function doesn’t change
give 2 thing that could happen if a mutation changes the shape of a proetin
an enzyme might not fit with the substrate binding site
and the structural protein could lose its strength
give an example of a piece of DNA which doesn’t code for proteins - what does it do?
non coding DNA - switches genes on and off
non coding genes (switching them on and off)could affect what
how the genes are expressed
what 2 things could a mutation do
change a coding gene
change a non coding gene - how expressed
could change phenotype or lead to genetic disease like cystic fibrosis
what is a gamete
sex cell
what is a chromosome
carries the DNA (genetic information)
what is an allele
a different version of the same gene
what does dominant mean
an allele that is always expressed even if only one copy is present
what is a recessive allele
only expressed if the individual has 2 copies of a gene
what does homozygous mean
alleles are identical
what is a phenotype
the observable physical characteristics of an organism
give 2 examples of characteristics controlled by a single gene
fur colour in mice and red green colour blindness in humans
what is the genotype
the alleles present
most characteristics are from one/many genes interacting
many
what is polydactly and what is it caused by
having extra fingers or toes
dominant
what is cystic fibrosis and what is it caused by
disorder of cell membranes
recessive
give 3 advantages and 3 disadvantages of embryonic screening
3 +
prevents suffering
financial benefits as don’t have to pay for long term treatment NHS
embryos in IVF need to be screened to check they are healthy
3 -
ethical concerns with destroying the embryos not used
designer babies
discrimination against characteristics or non designed people
expensive in the short term
how many pairs of chromosomes do human body cells have ordinarily
23
how many pairs determine sex
1
what is sex chromosomes for females
XX
sex chromosomes for males
XY
give 3 reasons for variations in characteristics of a population
genes
environment
combination of the two
how many genes roughly determine phenotype, how many influence it and what do most do
very few
some
no effect
what is the theory of evolution
all species evolved from simple life forms (that first developed more than 3 billion years ago)
when did simple life forms first develop
3 billion years ago
why does a new species happen
two populations of one species become so different in phenotype
that they can no longer interbreed to form fertile offspring
stages of evolution answer
mutation
variation (say what the variation is of)
competition
survival and reproduction as __is better suited to its environment!!
the allele is inherited over generations
evolution over time
what is selective breeding
when humans breed plants and animals for particular genetic charactertistics
when did humans first do selective breeding and give 2 examples
thousands of years ago
food crop breeding from wild plants
and domestication of animals
describe the process of selective breeding
choose parents with desired characteristic from a mixed population
breed them together
breed offspring with desired charactertistic together
continues over generations until all offspring show the desired charactertistic
give 4 examples of selective breeding for characteristics
disease resistance in food crops
animals producing more meat/milk
domestic dogs with gentle nature
large or unusual flowers
what bad thing can selective breeding lead to
inbreeding - where breeds are prone to disease or inherited defects
give 2 examples of genetic engineering in plants
engineered for disease resistance
and to produce bigger/better fruits
give an example of genetic engineering not in plants
bacterial cells engineered to produce useful substances like human insulin to treat diabetes
give 3 characteristics of GM crops
resistance to insect attack
resistance to herbicides
increased yeilds
give 2 concerns about GM crops
effects on wild flowers and insects as pollen could be toxic
effects of eating GM crops on human health haven’t been fully explored
what is modern medical research exploring with regards to genetic modification
exploring its usage to overcome genetic inherited disorders
give the 3 steps of genetic engineering
enzymes used to isolate gene
gene inserted into vector
vector inserts gene into cells
genes transferred to cells of organism at an early stage of the organisms development
what is used to isolate the required gene
enzymes
what is the gene inserted into in genetic engineering and what is this usually
vector - plasmid or virus
what is a tissue culture
using small groups of cells from the plant to grow identical new plants
give 2 uses of tissue cultures
preserving rare plant species
commercially in nurseries
cuttings is a new/old method and who is it used by and what for
old and simple
gardeners
producing many identical new plants from a parent plant
what are embryo transplants for cloning
split apart cells from developing animal embryo before specialised
transplant the identical embryos into host mothers
give the 5 stages of adult cell cloning
nucleus removed form unfertilised egg cell (enucleated)
nucleus from adult body cell(such as skin cell) inserted into egg cell
electric chock stimulates egg cell to divide into embryo
embryo has same genetic information as adult skin cell
when it has developed into ball it is inserted into womb of adult female to continue development
what is used to stimulate a clump of cels to divide into an embryo in adult cell cloning
electric shock
give 3 things that led Charles Darwin to his theory of evolution
observations on a round the world expedition
years of experimentation and discussion
linked to developing knowledge of geology and fossils
what did Darwin publish his ideas in and when
on the origin of species 1859
give 3 reasons there was controversy over evolution theory and it took a while for ideas to be accepted
challenged the idea that god created all animals and plants on earth
insufficient evidence at the time of publishing to convince many scientists
mechanism of inheritance and variation wasn’t known until 50 years after theory published
how many years after the theory of evolution was published was the mechanism of inheritance and evolution discovered
50
what is the theory of another guy around the time of Darwin and what was his name
Jean-Baptiste Lamarck
changes that occur in an organism during its lifetime can be inherited
why do we know Lamarck is wrong
for the vast majority of cases his type of inheritance of characteristics acquired in a lifetime cannot occur
who independent also proposed evolution by natural selection
Alfred Russel Wallace
who proposed joint writings with Darwin and when which promoted Darwin to do what
Alfred russel Wallace
1858
publish on the origin of species the following year
what is Alfred Russel Wallace best known for
warning colouration in animals
and speciation
what did Alfred Russel Wallace do
worked worldwide gathering evidence for evolutionary theory
who pioneered our understanding of speciation
Alfred russel Wallace
how does speciation happen
two populations separated
different mutations take place
natural selection makes them evolve differently
interbreeding can’t happen as phenotypes are too difference
what was Gregor Mendel up to until the mid 1850s
carrying out breeding experiments on plants
what was one observation from Gregor mendel
inheritance of characteristics is determined by ‘units’ that are passed on to descendants unchanged
when was the behaviour of chromosomes during cell division observed
the late 1800s
when was it observed that Mendel’s units and chromosomes behaved in similar ways and what did this lead to
early 1900s
units (genes)were located on chromosomes
when was the structure of DNA determined
mid 1900s
when was the mechanism of the gene function worked out
mid 20th century
give a timeline of gene theory
mendel units - 1850s
chromosomes - late 1800s
units are on chromosomes - early 1900s
mid 1900s - structure of DNA and gene function worked out
give 3 pieces of evidence for evolution
anti biotic resistant bacteria evolve
fossil records - show simple life
characteristics of parents are passed onto offspring in genes
what are fossils
the remains of organisms from millions of years ago found in rocks
give 3 ways fossils could be formed
parts of the organism haven’t decayed (as the conditions needed for decay are absent: no oxygen, no water, too cold)
parts of the organism replaced by minerals as they decay
preserved traces of organisms