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MOHD4: Exam 5 > Biological Rhythms > Flashcards

Biological Rhythms Flashcards

1
Q

Zeitgebers

A

light, food, activity

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2
Q

Intrinsically photosensitive

A

retinal ganglion

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3
Q

Responsible for generating circadian rhythms

A

suprachiasmatic nucleus

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4
Q

Associated with AD PER2 mutations

A

Advanced sleep phase disorder

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5
Q

Process S

A

Homeostatic need for sleep

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6
Q

Process C

A

circadian drive for arousal

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7
Q

May be caused by ATP breakdown and adenosine signaling

A

Sleep deprivation

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8
Q

Autoimmune destruction of orexin neurons

A

Narcolepsy

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9
Q

excessive daytime sleepiness, cataplexy, hypnagogig hallucinations, sleep paralysis, disturbed nocturnal sleep

A

Narcolepsy

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10
Q

Cardinal feature is reduced need for sleep

A

Bipolar disorder

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11
Q

Intrameal process that leads to termination of food intake

A

Satiety

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12
Q

Satiation

A

Process that controls intermeal interval

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13
Q

Grams of food consumed/intermeal interval

A

Satiety ratio

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14
Q

Meal phase: smell, sight, appeal, flavor, texture

A

Cognitive sensory

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15
Q

Meal phase: oral metering (sensory contact), osmotic load, gastric stretch

A

Pre-absorptive

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16
Q

Meal phase: nutrient absorption, digestive efficiency, neuroendocrine (CCK, insulin, GLPI)

A

Post-absorptive

17
Q

Functions of meals

A
  • Modulate nutrient intake
  • Social interaction
  • Set circadian rhythms
18
Q

Key hypothalamic player in feeding

A

Arcuate nucleus

19
Q

Inhibits feeding via aMSH acting on MC4R –> suppress food intake

A

POMC

20
Q

Common mutation in obesity

A

MC4R

21
Q

Promotes feeding via blocking MC4 receptor, blocking aMSH action

A

AgRP (agouti-related peptide)

22
Q

Release GABA to inhibit POMC neuron activity –> promote appetite

A

NPY

23
Q

Produced in stomach, pancreas, excitatory to NPY

A

Ghrelin

24
Q

Produced by adipose, excitatory to POMC, inhibitory to NPY

A

leptin

25
Q

Produced by duodenum, excitatory to POMC

A

Cholecystokinin

26
Q

Produced by pancreatic beta-cells, excitatory to POMC

A

Insulin

27
Q

Modafinil can treat

A

Narcolepsy, Shift work disorder

28
Q

Lisdexamfetamine can treat

A

Binge eating disorder

MOHD4: Exam 5 (23 decks)

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