biological approach in psycopathology Flashcards
what is the genetic explanation of OCD?
the greater the genetic relativeness the greater the chances of developing OCD
caused by mutated genes being passed on
Nedstadt et al found first degree relatives of OCD suffers had 12% chance of developing OCD compared to 3% of general pop
what gene can be impaired and effect the levels of serotonin?
SERT gene (5-HTT)
Research + of genetic explanations of OCD
genes can cause development for OCD….
greater genetic relativeness the greater the chances of developing OCD Nedstadt reviewed twins concordance of 0.67 but 0.31 for non-identical
Scientific + of genetic explanations of OCD
presents psychology as a scientific discipline as can be studied using DNA analysis and family history which is objective and reliable
Research - of genetic explanations of OCD
not only factor in developing OCD such as environmental factors causing genes to express themselves(Nedstadt study doesn’t have a 100% concordance rate)
Reductionist - of genetic explanations of OCD
biologically reductionist as ignores situational factors such as childhood trauma e.g strict parents
shows that the explanation is incomplete
What is the neural explanation of OCD?
The caudate nucleus doesn’t suppress the signal from the orbital frontal cortex to the Thalamus this creates a worry circuit as signal is continued to be sent back and forward
(e.g washing hands)
Research + of neural explanation of OCD
Ursu and Carter monitored brain activity in 15 OCD patients via FMRI which found hyperactivity in the OFC like the theory would suggest
theoretical - of neural explanation of OCD
the explanation is based off of a correlation so cause and effect cannot be established
low levels of serotonin and abnormal caudate nucleus are linked to OCD but it does not explain how it is developed so other factors may be responsible
example….
what do high levels of serotonin do?
prevent behaviour repeating
regulate mood by lowering anxiety and reducing depression
Practical application + of neural explanation of OCD
help 2-3% of society with OCD
by giving them antidepressants to increase their levels of serotonin to remove symptoms of OCD
and is effective for 70% of patients
What is drug therapy in terms of OCD treatment?
Increasing the level of neurotransmitters in the brain
such as serotonin
What is the serotonin antidepressant?
SSRI
Selective serotonin reuptake inhibitors
what is an example of an SSRI?
PROZAC
how do SSRI’s work?
block reuptake pumps on pre-synaptic neuron so less serotonin is recycled and remains in the synaptic gap
this reduces OCD symptoms