biological approach in psycopathology Flashcards

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1
Q

what is the genetic explanation of OCD?

A

the greater the genetic relativeness the greater the chances of developing OCD

caused by mutated genes being passed on

Nedstadt et al found first degree relatives of OCD suffers had 12% chance of developing OCD compared to 3% of general pop

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2
Q

what gene can be impaired and effect the levels of serotonin?

A

SERT gene (5-HTT)

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3
Q

Research + of genetic explanations of OCD

A

genes can cause development for OCD….
greater genetic relativeness the greater the chances of developing OCD Nedstadt reviewed twins concordance of 0.67 but 0.31 for non-identical

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4
Q

Scientific + of genetic explanations of OCD

A

presents psychology as a scientific discipline as can be studied using DNA analysis and family history which is objective and reliable

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5
Q

Research - of genetic explanations of OCD

A

not only factor in developing OCD such as environmental factors causing genes to express themselves(Nedstadt study doesn’t have a 100% concordance rate)

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6
Q

Reductionist - of genetic explanations of OCD

A

biologically reductionist as ignores situational factors such as childhood trauma e.g strict parents

shows that the explanation is incomplete

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7
Q

What is the neural explanation of OCD?

A

The caudate nucleus doesn’t suppress the signal from the orbital frontal cortex to the Thalamus this creates a worry circuit as signal is continued to be sent back and forward

(e.g washing hands)

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8
Q

Research + of neural explanation of OCD

A

Ursu and Carter monitored brain activity in 15 OCD patients via FMRI which found hyperactivity in the OFC like the theory would suggest

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9
Q

theoretical - of neural explanation of OCD

A

the explanation is based off of a correlation so cause and effect cannot be established
low levels of serotonin and abnormal caudate nucleus are linked to OCD but it does not explain how it is developed so other factors may be responsible

example….

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10
Q

what do high levels of serotonin do?

A

prevent behaviour repeating

regulate mood by lowering anxiety and reducing depression

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11
Q

Practical application + of neural explanation of OCD

A

help 2-3% of society with OCD
by giving them antidepressants to increase their levels of serotonin to remove symptoms of OCD
and is effective for 70% of patients

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12
Q

What is drug therapy in terms of OCD treatment?

A

Increasing the level of neurotransmitters in the brain

such as serotonin

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13
Q

What is the serotonin antidepressant?

A

SSRI

Selective serotonin reuptake inhibitors

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14
Q

what is an example of an SSRI?

A

PROZAC

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15
Q

how do SSRI’s work?

A

block reuptake pumps on pre-synaptic neuron so less serotonin is recycled and remains in the synaptic gap

this reduces OCD symptoms

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16
Q

what happens after 2 weeks of drug therapy in terms of OCD treatment?

A

neural adaption

17
Q

what type of drugs treat anxiety

A

antianxiety drugs e.g Valium which slow down brain communications = calming effect

18
Q

scientific Evidence + for drug therapy as a treatment for OCD

A

70% of patient’s OCD symptoms decline

SOOMRO found that pt’s in 17 studies of drug therapy showed improvement with SSRI’s compared to the placebo

19
Q

Long-term - for drug therapy as a treatment for OCD

A

Symptoms of OCD may decline but do not stop entirely

when patient stops taking the drug symptoms return and therefor patient can be come dependent

20
Q

scientific + for drug therapy as a treatment for OCD

A

drugs mode of action is objective and measurable for instance PET scans can monitor antidepressants on serotonin through cerebral fluid