BioEnergetics Of Exercise And Training Flashcards
___________ of exercise and training is based on an understanding of the transfer of energy in biological systems.
Metabolic Specificity
______________or the flow of energy in a biological system, concerns primarily the conversion of macronutrients- Carbs, fats, proteins.
Bioenergetics
The breakdown of large molecules into smaller molecules, associated with the release of energy, is termed _____________.
Catabolism
The synthesis of larger molecules from smaller molecules can be accomplished using the energy released from catabolic reaction. This building up process is called?
Anabolism
_______________ are energy-releasing reactions and are generally Catabolic.
Exergonic Reactions
______________ - require energy and include anabolic processes and the contraction of muscle.
Endergonic Reaction
______________ - is the total of all the catabolic or exergonic reactions is used to drive anabolic or endergonic reactions in a biological system.
Metabolism
______________ - energy derived from catabolic or exergonic reactions is used to drive anabolic or endergonic reactions through an intermediate molecule.
- Allows for the transfer of energy from exergonic to endergonic reactions.
- without as adequate supply, muscular activity and muscle growth would not be possible.
- Composed of adenosine and three phosphate groups
ATP
The breakdown of one molecule of ATP to yield energy is known as ________________.
Hydrolysis
The hydrolysis of ATP is catalyzed by the presence of enzyme called _________________________.
Adenosine Triphosphatase (ATPase)
________________ - pumping calcium into the sarcoplasmic reticulum
Calcium ATPase
_________________ - for maintaining the sarcolemmal concentration gradient after depolarization.
Sodium-potassium ATPase
________________ - ADP which only has two phosphate groups.
Adenosine Diphosphate.
Three basic energy systems exist in mammalian muscle cells to replenish ATP, they are?
- Phosphagen Sytem
- Glycolysis
- Oxidative system
The Kreb cycle, electron transport, and the rest of the oxidative system are aerobic mechanisms that occur in the ______________ of muscle cells and require oxygen as the terminal electron acceptor.
Mitochondria
Only _________________ can be metabolized for energy without the direct involvement of oxygen.
- it is critical during anaerobic metabolism
Carbs
______________ Provides ATP primarily for, short-term, high intensity activities and girly active at the start of all exercise regardless of intensity.
Phosphagen System
________________ also called ________________ is the enzyme tat catalyzes the synthesis at ATP from CP and ADP.
- supplies a phosphate group that combines with ADP to replenish ATP.
Creating Phosphate
The body stores approximately ______ to _______g of ATP at any give time, which does not represent a significant energy reserve for exercise.
80 to 100g
_______ stores cannot be completely depleted due to the necessity for basic cellular function.
-In fact, concentrations may decrease by up to 50 to 60% of the prexercise levels during experimentally induced muscle fatigue. This is why Phosphagen systems use the creative kinase reaction to maintain the concentration of ____.
ATP
Another important single-enzyme reaction that can rapidly replenish ATP is the __________________
- this reaction is particularly important because AMP, a product of the adenylate kinase reaction, is a powerful stimulant of glycolysis.
Adenylate Kinases (also called MYOKINASE) Reaction.
The reactions of Phosphagen system are largely controlled by the _______________ or mass action effect.
-states that the concentrations of reactants or products in solution will drive the direction of the reactions.
Law of Mass Action
________________ that proceed in a direction dictated by the concentrations of the reactants due to the law of mass action.
Near-equilibrium reaction
_____________ , the end result of glycolysis, may proceed in one of two directions:
- Can be converted to lactate in the sarcoplasm
- Can be shuttled into the mitochondria.
Pyruvate
When pyruvate is converted to lactate, ATP resynthesis occurs at a faster rate via the rapid regeneration of NAD+, but is limited in duration due to the subsequent H+ production and resulting decrease in cytosolic pH. This is called _________________
Anaerobic glycolysis
However, when pyruvate is shuttled into the mitochondria to undergo the Krebs cycle, the ATP resynthesis rate is slower because of the numerous reactions, but can occur for a longer duration if the exercise intensity is low enough. This process is often referred to as _____________________.
Aerobic Glycolysis
The formation of lactate from pyruvate is catalyzed by the enzyme __________________.
Lactate dehydrogenase
Due to the physiological pH and earlier steps in glycolysis that consume protons, ____________ - rather than lactic acid — is the product of the lactate dehydrogenase reaction.
Lactate
This process of an exercise-indices decrease in pHis referred to as _____________________, and may be responsible for much of the peripheral fatigue that occurs during exercise.
Metabolic Acidosis
Lactate is often used as an __________________, especially in type 1 and cardiac muscle fibers.
Energy substrate
It is also used in ____________ - the formation of glucose from noncarbohydrate sources — during extended exercise and recovery.
Gluconeogenesis
_____________ - muscle that has not been desiccated
Wet muscle
Lactate can also be transported in the blood to the liver, where it is converted to glucose. This process is called______________.
Cori Cycle
the net reaction for glycolysis when pyruvate is converted to lactate may be summarized as follows:
____________+____+______——> ________ + _______ + ________
Glucose + 2Pi + 2ADP —> 2Lactate +2ATP +H2O